Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR4 | O00206 | 1/20 | 0.53 |
| ▸ | TLR2 | O60603 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | LTA4H | P09960 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | EPOR | P19235 | 1/20 | 0.46 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.46 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.44 |
| ▸ | MMP3 | P08254 | 1/20 | 0.44 |
| ▸ | MMP13 | P45452 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL34465491 | 1.00 | TLR4 (0.53) | TLR4TLR2TSHRALDH1A1LTA4H | |
| SCHEMBL27656980 | 0.94 | TDP1 (0.52) | TLR4TLR2TSHRALDH1A1MAOB | |
| SCHEMBL31236273 | 0.94 | TDP1 (0.52) | TLR4TLR2TSHRALDH1A1MAOB | |
| Diphenylether SCHEMBL787546 | 0.87 | TSHR (0.70) | TLR4TLR2TSHRALDH1A1LTA4H | |
| SCHEMBL942948 | 0.85 | LTA4H (0.52) | TLR4TLR2TSHRALDH1A1LTA4H | |
| SCHEMBL9161972 | 0.85 | NFE2L2 (0.47) | TLR4TLR2TSHRALDH1A1MAOB | |
| SCHEMBL14612623 | 0.85 | RELA (0.56) | ALDH1A1LTA4HMAOBMAPTTP53 | |
| SCHEMBL14612631 | 0.85 | TDP1 (0.55) | TLR4TLR2ALDH1A1MAOBALOX5 | |
| SCHEMBL8778154 | 0.85 | ALDH1A1 (0.55) | TLR4TLR2ALDH1A1MAOBALOX5 | |
| Diphenylether SCHEMBL28210841 | 0.85 | TSHR (0.67) | TLR4TLR2TSHRALDH1A1LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 342 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260003210-A1 | DIFFRACTIVE CONTACT LENSES | ALCON INC (CH) | 2026-01-01 | — | — | US | claimed |
| US-12379611-B2 | Diffractive contact lenses | ALCON INC. (CH) | 2025-08-05 | — | — | US | claimed |
| EP-4356169-A1 | MULTIFOCAL DIFFRACTIVE SILICONE HYDROGEL CONTACT LENSES | Alcon Inc. (CH) | 2024-04-24 | — | — | EP | claimed |
| CN-117280252-A | Multifocal diffractive silicone hydrogel contact lenses | 爱尔康公司 | 2023-12-22 | — | — | CN | claimed |
| US-20230004023-A1 | DIFFRACTIVE CONTACT LENSES | ALCON INC. (CH) | 2023-01-05 | — | — | US | claimed |
| WO-2022263994-A1 | MULTIFOCAL DIFFRACTIVE SILICONE HYDROGEL CONTACT LENSES | ALCON INC. (CH) | 2022-12-22 | — | — | WO | claimed |
| US-7015360-B2 | Asymmetric catalysts prepared from optically active bisphosphites bridged by achiral diols | DOW GLOBAL TECHNOLOGIES, INC. (US) | 2006-03-21 | — | — | US | claimed |
| EP-1611145-A2 | ASYMMETRIC CATALYSTS PREPARED FROM OPTICALLY ACTIVE BISPHOSPHITES BRIDGED BY ACHIRAL DIOLS | DOW GLOBAL TECHNOLOGIES INC. (US) | 2006-01-04 | — | — | EP | claimed |
| WO-2004094442-A2 | ASYMMETRIC CATALYSTS PREPARED FROM OPTICALLY ACTIVE BISPHOSPHITES BRIDGED BY ACHIRAL DIOLS | DOW GLOBAL TECHNOLOGIES INC. (US) | 2004-11-04 | — | — | WO | claimed |
| US-20040199023-A1 | Asymmetric catalysts prepared from optically active bisphosphites bridged by achiral diols | DOW GLOBAL TECHNOLOGIES INC. | 2004-10-07 | — | — | US | claimed |
| WO-1997014669-A1 | PROCESS FOR PREPARING OPTICALLY ACTIVE CARBOXYLIC ACIDS | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 1997-04-24 | — | — | WO | claimed |
| EP-0766658-A1 | PROCESS FOR IMPROVING ENANTIOMERIC PURITY OF ALDEHYDES | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 1997-04-09 | — | — | EP | claimed |
| US-5602267-A | Organometallic catalysts for epoxidizing prochiral olefins and a new class of amid-salicylidene ligands | HOECHST CELANESE (US) | 1997-02-11 | — | — | US | claimed |
| US-5491266-A | REACTING CHIRAL COMPOUND IN PRESENCE OF OPTICALLY ACTIVE METAL-LIGAND COMPLEX | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 1996-02-13 | — | — | US | claimed |
| EP-0600020-B1 | ASYMMETRIC SYNTHESES | UNION CARBIDE CHEM PLASTIC (US) | 1996-01-31 | — | — | EP | claimed |
| WO-1996000200-A1 | PROCESS FOR IMPROVING ENANTIOMERIC PURITY OF ALDEHYDES | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 1996-01-04 | — | — | WO | claimed |
| US-5430194-A | Maintaining solution at temperature above eutectic temperature of mixture such that solubility limit of first aldehyde is exceeded to form crystalline first aldehyde containing less of second aldehyde | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 1995-07-04 | — | — | US | claimed |
| EP-0600020-A1 | ASYMMETRIC SYNTHESES. | UNION CARBIDE CHEM PLASTIC (US) | 1994-06-08 | — | — | EP | claimed |
| CN-1071431-A | Asymmetric synthesis | UNION CARBIDE CHEM PLASTIC (US) | 1993-04-28 | — | — | CN | claimed |
| WO-1993003839-A1 | ASYMMETRIC SYNTHESES | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 1993-03-04 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040199023-A1 | Asymmetric catalysts prepared from optically active bisphosphites bridged by achiral diols | ALDH3A1, APEH, DPYD | TLR4 4658/4885TLR2 4560/4885TSHR 3139/4885 |
| US-20260003210-A1 | DIFFRACTIVE CONTACT LENSES | LBR, CRYZ, CRYAA | TLR4 537/4885TLR2 338/4885TSHR 1437/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.