Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HNF4A | P41235 | 2/20 | 0.51 |
| ▸ | ERN1 | O75460 | 2/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.47 |
| ▸ | PTPN6 | P29350 | 2/20 | 0.47 |
| ▸ | AKR1C2 | P52895 | 4/20 | 0.43 |
| ▸ | AKR1C1 | Q04828 | 4/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.43 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.42 |
| ▸ | LDHA | P00338 | 1/20 | 0.40 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.40 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.39 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.39 |
| ▸ | SELL | P14151 | 1/20 | 0.38 |
| ▸ | SELP | P16109 | 1/20 | 0.38 |
| ▸ | PIM1 | P11309 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6537038 | 0.76 | HNF4A (0.71) | HNF4APTPN1PTPN6AKR1C2AKR1C1 | |
| SCHEMBL14690430 | 0.75 | HNF4A (0.59) | HNF4APTPN1PTPN6AKR1C2AKR1C1 | |
| SCHEMBL8001214 | 0.73 | HNF4A (0.67) | HNF4APTPN1PTPN6AKR1C2AKR1C1 | |
| SCHEMBL28173339 | 0.71 | HNF4A (0.59) | HNF4APTPN1PTPN6AKR1C2AKR1C1 | |
| SCHEMBL548758 | 0.71 | ERN1 (0.50) | HNF4AERN1PTPN1PTPN6AKR1C2 | |
| SCHEMBL14689569 | 0.71 | MAPT (0.60) | HNF4APTPN1PTPN6AKR1C2AKR1C1 | |
| SCHEMBL9378287 | 0.71 | HNF4A (0.59) | HNF4APTPN1PTPN6AKR1C2AKR1C1 | |
| SCHEMBL16296809 | 0.69 | ESR2 (0.40) | ALDH1A1KDM4E | |
| SCHEMBL27718219 | 0.69 | HNF4A (0.61) | HNF4APTPN1PTPN6AKR1C2AKR1C1 | |
| SCHEMBL6548166 | 0.69 | KDM4E (0.40) | ALDH1A1KDM4EHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2036946-B1 | Radiation resistant resin composition and radiation-proof wire/cable | FUJIKURA LTD (JP) | 2015-06-17 | — | — | EP | disclosed |
| EP-2036946-A1 | Radiation resistant resin composition and radiation-proof wire/cable | FUJIKURA LTD. (JP) | 2009-03-18 | — | — | EP | disclosed |