Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 4/20 | 0.32 |
| ▸ | RXRA | P19793 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4553657 | 0.95 | SMN1; SMN2 (0.51) | SMN1; SMN2LMNAHTTALDH1A1MAPT | |
| SCHEMBL2230968 | 0.94 | SMN1; SMN2 (0.51) | SMN1; SMN2LMNAHTTALDH1A1MAPT | |
| SCHEMBL2231616 | 0.91 | SMN1; SMN2 (0.53) | SMN1; SMN2LMNAHTTALDH1A1MAPT | |
| SCHEMBL1647394 | 0.91 | SMN1; SMN2 (0.51) | SMN1; SMN2LMNAHTTALDH1A1MAPT | |
| SCHEMBL1646524 | 0.88 | LMNA (0.43) | SMN1; SMN2LMNAHTTALDH1A1MAPT | |
| SCHEMBL1647340 | 0.87 | SMN1; SMN2 (0.52) | SMN1; SMN2LMNAHTTALDH1A1MAPT | |
| SCHEMBL2231005 | 0.87 | LMNA (0.43) | SMN1; SMN2LMNAHTTALDH1A1MAPT | |
| SCHEMBL1646520 | 0.85 | SMN1; SMN2 (0.50) | SMN1; SMN2LMNAHTTALDH1A1MAPT | |
| SCHEMBL4553332 | 0.85 | SMN1; SMN2 (0.47) | SMN1; SMN2LMNAHTTALDH1A1MAPT | |
| SCHEMBL4553661 | 0.85 | SMN1; SMN2 (0.52) | SMN1; SMN2LMNAHTTALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2097413-A1 | 2-[(2-SUBSTITUTED)-IND0LIZIN-3-YL]-2-OXO-ACETAMIDE DERIVATIVES AS ANTIFUNGAL AGENTS | F2G Limited (GB) | 2009-09-09 | — | — | EP | disclosed |
| WO-2008062182-A1 | 2- [ (2-SUBSTITUTED) -IND0LIZIN-3-YL] -2-OXO-ACETAMIDE DERIVATIVES AS ANTIFUNGAL AGENTS | F2G LTD (GB) | 2008-05-29 | — | — | WO | disclosed |