Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4554772 | 0.93 | POLB (0.33) | POLB | |
| SCHEMBL4555092 | 0.89 | POLB (0.34) | POLB | |
| SCHEMBL4553475 | 0.83 | POLB (0.34) | POLB | |
| SCHEMBL4554771 | 0.79 | POLB (0.33) | POLB | |
| SCHEMBL963830 | 0.77 | POLB (0.33) | POLB | |
| SCHEMBL4555091 | 0.76 | POLB (0.34) | POLB | |
| SCHEMBL4553884 | 0.72 | IRAK4 (0.33) | — | |
| SCHEMBL27793916 | 0.72 | MCHR1 (0.33) | — | |
| SCHEMBL962680 | 0.70 | ALDH1A1 (0.33) | POLB | |
| SCHEMBL961987 | 0.70 | POLB (0.34) | POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2118066-A1 | FUSED RING COMPOUNDS AS PARTIAL AGONISTS OF PPAR-GAMMA | Takeda Pharmaceutical Company Limited (JP) | 2009-11-18 | — | — | EP | disclosed |
| WO-2008099794-A1 | FUSED RING COMPOUNDS AS PARTIAL AGONISTS OF PPAR-GAMMA | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-08-21 | — | — | WO | disclosed |