Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 17/20 | 0.42 |
| ▸ | CA2 | P00918 | 17/20 | 0.42 |
| ▸ | CA4 | P22748 | 3/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4553508 | 1.00 | CA1 (0.42) | CA1CA2CA4CA12CA7 | |
| SCHEMBL4555340 | 0.91 | CA1 (0.42) | CA1CA2CA4CA12CA7 | |
| SCHEMBL4555343 | 0.91 | CA1 (0.42) | CA1CA2CA4CA12CA7 | |
| SCHEMBL4555511 | 0.91 | CA1 (0.42) | CA1CA2CA4CA12CA7 | |
| SCHEMBL4554532 | 0.91 | CA1 (0.42) | CA1CA2CA4CA12CA7 | |
| SCHEMBL4555512 | 0.91 | CA1 (0.42) | CA1CA2CA4CA12CA7 | |
| SCHEMBL4554531 | 0.91 | CA1 (0.42) | CA1CA2CA4CA12CA7 | |
| SCHEMBL3765266 | 0.89 | CA1 (0.42) | CA1CA2CA4CA12CA7 | |
| SCHEMBL3765269 | 0.89 | CA1 (0.42) | CA1CA2CA4CA12CA7 | |
| SCHEMBL4554498 | 0.89 | CA2 (0.42) | CA1CA2CA4CA12CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2129666-A2 | DEVELOPMENT OF MOLECULAR IMAGING PROBES FOR CARBONIC ANHYDRASE-IX USING CLICK CHEMISTRY | Siemens Medical Solutions USA, Inc. (US) | 2009-12-09 | — | — | EP | claimed |
| WO-2008124703-A2 | DEVELOPMENT OF MOLECULAR IMAGING PROBES FOR CARBONIC ANHYDRASE-IX USING CLICK CHEMISTRY | SIEMENS MEDICAL SOLUTIONS USA, INC. (US) | 2008-10-16 | — | — | WO | claimed |
| EP-2129666-A2 | DEVELOPMENT OF MOLECULAR IMAGING PROBES FOR CARBONIC ANHYDRASE-IX USING CLICK CHEMISTRY | Siemens Medical Solutions USA, Inc. (US) | 2009-12-09 | — | — | EP | disclosed |
| WO-2008124703-A2 | DEVELOPMENT OF MOLECULAR IMAGING PROBES FOR CARBONIC ANHYDRASE-IX USING CLICK CHEMISTRY | SIEMENS MEDICAL SOLUTIONS USA, INC. (US) | 2008-10-16 | — | — | WO | disclosed |