Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 2/20 | 0.47 |
| ▸ | NAAA | Q02083 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1584701 | 0.85 | EPHX1 (0.52) | EPHX1NAAAHTTSMN1; SMN2CYP2C19 | |
| SCHEMBL27595620 | 0.83 | EPHX1 (0.48) | EPHX1NAAAHTTSMN1; SMN2CYP2C19 | |
| SCHEMBL2059955 | 0.81 | ALDH1A1 (0.56) | EPHX1NAAAHTTSMN1; SMN2CYP2C19 | |
| SCHEMBL974950 | 0.81 | ALDH1A1 (0.56) | EPHX1NAAAHTTSMN1; SMN2CYP2C19 | |
| SCHEMBL28271240 | 0.81 | EPHX1 (0.44) | EPHX1NAAAHTTSMN1; SMN2CYP2C19 | |
| SCHEMBL4672536 | 0.81 | EPHX1 (0.50) | EPHX1NAAAHTTSMN1; SMN2CYP2C19 | |
| SCHEMBL7814661 | 0.79 | EPHX1 (0.47) | EPHX1NAAAHTTSMN1; SMN2CYP2C19 | |
| SCHEMBL755855 | 0.79 | EPHX1 (0.48) | EPHX1NAAAHTTSMN1; SMN2CYP2C19 | |
| SCHEMBL28168096 | 0.79 | EPHX1 (0.44) | EPHX1NAAAHTTSMN1; SMN2CYP2C19 | |
| SCHEMBL4676851 | 0.78 | EPHX1 (0.47) | EPHX1NAAAHTTSMN1; SMN2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2114437-A2 | MODIFIED CORTICOTROPIN RELEASING FACTOR PEPTIDES AND USES THEREOF | ConjuChem Biotechnologies Inc. (CA) | 2009-11-11 | — | — | EP | disclosed |
| WO-2008047241-A2 | MODIFIED CORTICOTROPIN RELEASING FACTOR PEPTIDES AND USES THEREOF | CONJUCHEM BIOTECHNOLOGIES INC. (US) | 2008-04-24 | — | — | WO | disclosed |