Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | SI | P14410 | 1/20 | 0.35 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27650612 | 0.86 | CYP2C19 (0.33) | TSHRALDH1A1USP2LMNACYP1A2 | |
| SCHEMBL22478769 | 0.83 | ALDH1A1 (0.39) | MGAMGAASIMGAM2CYP3A4 | |
| SCHEMBL14514434 | 0.82 | TP53 (0.36) | MGAMGAASIMGAM2TP53 | |
| SCHEMBL10822838 | 0.82 | KDM4E (0.40) | MGAMGAASIMGAM2TSHR | |
| SCHEMBL22478783 | 0.81 | ALDH1A1 (0.41) | MGAMGAASIMGAM2CYP3A4 | |
| SCHEMBL28758873 | 0.78 | NPSR1 (0.32) | MGAMGAASIMGAM2CYP3A4 | |
| SCHEMBL3692669 | 0.78 | CYP3A4 (0.35) | MGAMGAASIMGAM2CYP3A4 | |
| SCHEMBL7111915 | 0.77 | TSHR (0.37) | GAATSHRALDH1A1NPSR1MEN1 | |
| SCHEMBL13649534 | 0.76 | ALDH1A1 (0.32) | TSHRALDH1A1LMNACYP2C19HSD17B10 | |
| SCHEMBL14883391 | 0.76 | ALDH1A1 (0.32) | TSHRALDH1A1LMNACYP2C19HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2114437-A2 | MODIFIED CORTICOTROPIN RELEASING FACTOR PEPTIDES AND USES THEREOF | ConjuChem Biotechnologies Inc. (CA) | 2009-11-11 | — | — | EP | disclosed |
| WO-2008047241-A2 | MODIFIED CORTICOTROPIN RELEASING FACTOR PEPTIDES AND USES THEREOF | CONJUCHEM BIOTECHNOLOGIES INC. (US) | 2008-04-24 | — | — | WO | disclosed |