Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | HTT | P42858 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 6/20 | 0.42 |
| ▸ | RAB9A | P51151 | 6/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | HTR1D | P28221 | 1/20 | 0.41 |
| ▸ | HTR1B | P28222 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1647320 | 0.92 | ALDH1A1 (0.56) | MAPTALDH1A1LMNAHTTSMN1; SMN2 | |
| SCHEMBL1646045 | 0.91 | MAPT (0.58) | MAPTALDH1A1LMNAHTTSMN1; SMN2 | |
| SCHEMBL1644528 | 0.87 | ALDH1A1 (0.54) | MAPTALDH1A1LMNAHTTSMN1; SMN2 | |
| SCHEMBL1645570 | 0.82 | MAPT (0.58) | MAPTALDH1A1LMNAHTTSMN1; SMN2 | |
| SCHEMBL1644926 | 0.81 | MAPT (0.58) | MAPTALDH1A1LMNAHTTSMN1; SMN2 | |
| SCHEMBL1645536 | 0.81 | MAPT (0.57) | MAPTALDH1A1LMNAHTTSMN1; SMN2 | |
| SCHEMBL1645535 | 0.81 | MAPT (0.55) | MAPTALDH1A1LMNAHTTSMN1; SMN2 | |
| SCHEMBL2231595 | 0.81 | ALDH1A1 (0.55) | MAPTALDH1A1LMNAHTTSMN1; SMN2 | |
| SCHEMBL1646414 | 0.81 | MAPT (0.66) | MAPTALDH1A1LMNAHTTSMN1; SMN2 | |
| SCHEMBL1646528 | 0.80 | ALDH1A1 (0.55) | MAPTALDH1A1LMNAHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2097413-A1 | 2-[(2-SUBSTITUTED)-IND0LIZIN-3-YL]-2-OXO-ACETAMIDE DERIVATIVES AS ANTIFUNGAL AGENTS | F2G Limited (GB) | 2009-09-09 | — | — | EP | disclosed |
| WO-2008062182-A1 | 2- [ (2-SUBSTITUTED) -IND0LIZIN-3-YL] -2-OXO-ACETAMIDE DERIVATIVES AS ANTIFUNGAL AGENTS | F2G LTD (GB) | 2008-05-29 | — | — | WO | disclosed |