Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TYMP | P19971 | 2/20 | 0.37 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.36 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | POLA1 | P09884 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | PDE9A | O76083 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.31 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2113125 | 0.89 | KDM4E (0.49) | KDM4EALDH1A1TYMPTAS1R3TAS1R1 | |
| SCHEMBL7534659 | 0.89 | KDM4E (0.49) | KDM4EALDH1A1TYMPTAS1R3TAS1R1 | |
| SCHEMBL10490993 | 0.88 | HPGD (0.44) | TYMPTAS1R3TAS1R1TAAR1HPGD | |
| SCHEMBL5133061 | 0.88 | KDM4E (0.53) | KDM4EALDH1A1TYMPTAS1R3TAS1R1 | |
| SCHEMBL11130624 | 0.86 | KDM4E (0.48) | KDM4EALDH1A1TYMPTAS1R3TAS1R1 | |
| SCHEMBL11281236 | 0.84 | KDM4E (0.46) | KDM4ETYMPTAS1R3TAS1R1POLA1 | |
| SCHEMBL17222397 | 0.83 | KDM4E (0.47) | KDM4ETYMPTAS1R3TAS1R1POLA1 | |
| SCHEMBL441421 | 0.83 | TYMP (0.48) | KDM4ETYMPTAS1R3TAS1R1TAAR1 | |
| SCHEMBL6841553 | 0.82 | KDM4E (0.46) | KDM4EALDH1A1TYMPTAS1R3TAS1R1 | |
| SCHEMBL4434106 | 0.82 | ADORA2A (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080125327-A1 | Bonding amino moieties to solid surface with reactive hydroxyl groups, bonding succinate moieties to the amine groups through amide bonds to form cleavable linkers attached to the solid surface, bonding a succinate group, a sugar group and a base group, synthesizing oligonucleotides | CUSTOMARRAY, INC. | 2008-05-29 | — | — | US | claimed |
| US-20070065877-A1 | Microarray having a base cleavable succinate linker | COMBIMATRIX CORPORATION | 2007-03-22 | — | — | US | claimed |
| US-20190227060-A1 | MICROARRAY HAVING A BASE CLEAVABLE LINKER | CUSTOMARRAY, INC. (US) | 2019-07-25 | — | — | US | disclosed |
| US-10261075-B2 | Microarray having a base cleavable linker | CUSTOMARRAY, INC. (US) | 2019-04-16 | — | — | US | disclosed |
| US-20180267032-A1 | Microarray Having a Base Cleavable Linker | CUSTOMARRAY, INC. (US) | 2018-09-20 | — | — | US | disclosed |
| US-9983204-B2 | Microarray having a base cleavable linker | CUSTOMARRAY, INC. (US) | 2018-05-29 | — | — | US | disclosed |
| US-20090280998-A1 | Microarray having a base cleavable linker | CUSTOMARRAY, INC. | 2009-11-12 | — | — | US | disclosed |
| US-20080125327-A1 | Bonding amino moieties to solid surface with reactive hydroxyl groups, bonding succinate moieties to the amine groups through amide bonds to form cleavable linkers attached to the solid surface, bonding a succinate group, a sugar group and a base group, synthesizing oligonucleotides | CUSTOMARRAY, INC. | 2008-05-29 | — | — | US | disclosed |
| US-20070065877-A1 | Microarray having a base cleavable succinate linker | COMBIMATRIX CORPORATION | 2007-03-22 | — | — | US | disclosed |