Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 7/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.42 |
| ▸ | HTT | P42858 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 8/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | CASR | P41180 | 1/20 | 0.30 |
| ▸ | GBA1 | P04062 | 1/20 | 0.30 |
| ▸ | PHGDH | O43175 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2232559 | 0.93 | LMNA (0.42) | LMNASMN1; SMN2HTTMAPTALDH1A1 | |
| SCHEMBL1644600 | 0.91 | SMN1; SMN2 (0.41) | LMNASMN1; SMN2HTTMAPTALDH1A1 | |
| SCHEMBL1647300 | 0.90 | SMN1; SMN2 (0.51) | LMNASMN1; SMN2HTTMAPTALDH1A1 | |
| SCHEMBL2231070 | 0.89 | LMNA (0.40) | LMNASMN1; SMN2HTTMAPTALDH1A1 | |
| SCHEMBL1645552 | 0.87 | SMN1; SMN2 (0.43) | LMNASMN1; SMN2HTTMAPTALDH1A1 | |
| SCHEMBL1989148 | 0.84 | SMN1; SMN2 (0.36) | LMNASMN1; SMN2HTTMAPTALDH1A1 | |
| SCHEMBL2232421 | 0.84 | SMN1; SMN2 (0.39) | LMNASMN1; SMN2HTTMAPTALDH1A1 | |
| SCHEMBL2230727 | 0.82 | SMN1; SMN2 (0.42) | LMNASMN1; SMN2HTTMAPTALDH1A1 | |
| SCHEMBL1644586 | 0.81 | LMNA (0.44) | LMNASMN1; SMN2HTTMAPTALDH1A1 | |
| SCHEMBL1646507 | 0.80 | LMNA (0.43) | LMNASMN1; SMN2HTTMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2097413-A1 | 2-[(2-SUBSTITUTED)-IND0LIZIN-3-YL]-2-OXO-ACETAMIDE DERIVATIVES AS ANTIFUNGAL AGENTS | F2G Limited (GB) | 2009-09-09 | — | — | EP | disclosed |
| WO-2008062182-A1 | 2- [ (2-SUBSTITUTED) -IND0LIZIN-3-YL] -2-OXO-ACETAMIDE DERIVATIVES AS ANTIFUNGAL AGENTS | F2G LTD (GB) | 2008-05-29 | — | — | WO | disclosed |