Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3726774 | 0.80 | — | — | |
| SCHEMBL844057 | 0.69 | CYP3A4 (0.39) | CYP3A4 | |
| SCHEMBL105404 | 0.67 | CYP3A4 (0.47) | CYP3A4 | |
| SCHEMBL5744126 | 0.63 | CTNNB1 (0.42) | CYP3A4 | |
| SCHEMBL3577706 | 0.61 | PARP1 (0.45) | — | |
| SCHEMBL24400758 | 0.60 | MRGPRX4 (0.38) | CYP3A4 | |
| SCHEMBL9686722 | 0.60 | SMN1; SMN2 (0.40) | CYP3A4 | |
| SCHEMBL24400748 | 0.59 | ALDH1A1 (0.39) | CYP3A4 | |
| SCHEMBL2937583 | 0.58 | EGFR (0.41) | — | |
| SCHEMBL2382926 | 0.58 | MAPK1 (0.54) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2136807-A1 | PYRROLO (3, 2, 1-IJ) QUINOLINE-4-ONE DERIVATIVES FOR TREATING TUBERCULOSIS | Glaxo Group Limited (GB) | 2009-12-30 | — | — | EP | disclosed |
| WO-2008125594-A1 | PYRROLO (3, 2, 1-IJ) QUINOLINE-4-ONE DERIVATIVES FOR TREATING TUBERCULOSIS | GLAXO GROUP LIMITED (GB) | 2008-10-23 | — | — | WO | disclosed |