Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 4/20 | 1.00 |
| ▸ | HTR6 | P50406 | 3/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.40 |
| ▸ | AADAT | Q8N5Z0 | 2/20 | 0.39 |
| ▸ | GOT1 | P17174 | 1/20 | 0.39 |
| ▸ | KYAT1 | Q16773 | 1/20 | 0.39 |
| ▸ | KYAT3 | Q6YP21 | 1/20 | 0.39 |
| ▸ | OXTR | P30559 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29896718 | 1.00 | NOTUM (1.00) | NOTUMHTR6OPRM1OPRK1OPRL1 | |
| SCHEMBL21839107 | 1.00 | NOTUM (1.00) | NOTUMHTR6OPRM1OPRK1OPRL1 | |
| SCHEMBL17382966 | 1.00 | NOTUM (1.00) | NOTUMHTR6OPRM1OPRK1OPRL1 | |
| SCHEMBL7310227 | 0.83 | NOTUM (0.71) | NOTUMHTR6OPRM1OPRK1OPRL1 | |
| SCHEMBL31091230 | 0.75 | NOTUM (0.60) | NOTUMOPRM1OPRK1OPRL1AADAT | |
| SCHEMBL31091229 | 0.75 | NOTUM (0.60) | NOTUMOPRM1OPRK1OPRL1AADAT | |
| SCHEMBL157086 | 0.75 | NOTUM (0.60) | NOTUMOPRM1OPRK1OPRL1AADAT | |
| SCHEMBL17372888 | 0.74 | NOTUM (0.58) | NOTUMAADATGOT1KYAT1KYAT3 | |
| SCHEMBL17372889 | 0.74 | NOTUM (0.58) | NOTUMAADATGOT1KYAT1KYAT3 | |
| SCHEMBL21839140 | 0.73 | NOTUM (0.57) | NOTUMHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2134721-A1 | ANTIMICROBIAL HETEROCYCLIC COMPOUNDS FOR TREATMENT OF BACTERIAL INFECTIONS | Micurx Pharmaceuticals, Inc. (US) | 2009-12-23 | — | — | EP | disclosed |
| WO-2008108988-A1 | ANTIMICROBIAL HETEROCYCLIC COMPOUNDS FOR TREATMENT OF BACTERIAL INFECTIONS | MICURX PHARMACEUTICALS, INC. (US) | 2008-09-12 | — | — | WO | disclosed |