Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Salicylic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 1.00 |
| ▸ | HPGD | P15428 | 5/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | CA2 | P00918 | 2/20 | 0.58 |
| ▸ | CA4 | P22748 | 2/20 | 0.58 |
| ▸ | CA1 | P00915 | 2/20 | 0.58 |
| ▸ | CA9 | Q16790 | 2/20 | 0.58 |
| ▸ | CA12 | O43570 | 1/20 | 0.58 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.58 |
| ▸ | CA6 | P23280 | 1/20 | 0.58 |
| ▸ | CA7 | P43166 | 1/20 | 0.58 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.58 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | MPO | P05164 | 1/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Salicylic Acid SCHEMBL16116234 | 1.00 | KDM4E (1.00) | KDM4EHPGDALDH1A1SMN1; SMN2CA2 | |
| Salicylic Acid SCHEMBL10793800 | 1.00 | KDM4E (1.00) | KDM4EHPGDALDH1A1SMN1; SMN2CA2 | |
| Salicylic Acid SCHEMBL4603 | 1.00 | KDM4E (1.00) | KDM4EHPGDALDH1A1SMN1; SMN2CA2 | |
| Salicylic Acid SCHEMBL28341718 | 1.00 | KDM4E (1.00) | KDM4EHPGDALDH1A1SMN1; SMN2CA2 | |
| Salicylic Acid SCHEMBL29888959 | 1.00 | KDM4E (1.00) | KDM4EHPGDALDH1A1SMN1; SMN2CA2 | |
| Salicylic Acid SCHEMBL10708399 | 0.98 | KDM4E (0.95) | KDM4EHPGDALDH1A1SMN1; SMN2CA2 | |
| Salicylic Acid SCHEMBL3312655 | 0.98 | KDM4E (0.95) | KDM4EHPGDALDH1A1SMN1; SMN2CA2 | |
| Salicylic Acid SCHEMBL5450889 | 0.98 | KDM4E (0.95) | KDM4EHPGDALDH1A1SMN1; SMN2CA2 | |
| Salicylic Acid SCHEMBL8683263 | 0.98 | KDM4E (0.95) | KDM4EHPGDALDH1A1SMN1; SMN2CA2 | |
| Salicylic Acid SCHEMBL31668375 | 0.98 | KDM4E (0.95) | KDM4EHPGDALDH1A1SMN1; SMN2CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110573564-B | Process for preparing halogenated isobutylene-isoprene rubber | 信实工业公司 | 2022-02-18 | — | — | CN | claimed |
| CN-110922728-A | Organic nucleating agent for preparing heat-resistant polylactic resin and preparation method thereof | 蚌埠学院 | 2020-03-27 | — | — | CN | claimed |
| US-7271253-B1 | Safe process for the preparation of balsalazide | APOTEX PHARMACHEM INC. (CA) | 2007-09-18 | — | — | US | claimed |
| CN-119744178-A | Combination of AKR1C 3-activated anticancer prodrug compounds and analgesic drugs for the treatment of cancer patients with pain | 深圳艾欣达伟医药科技有限公司 | 2025-04-01 | — | — | CN | disclosed |
| CN-119677515-A | Treatment of fibrotic diseases using metabotropic glutamate receptor 5 antagonists or/and cannabinoid receptor 1 antagonists | 美国政府健康及人类服务部 | 2025-03-21 | — | — | CN | disclosed |
| CN-119191941-A | Separation method and application of CBDO isomer | 中国科学院宁波材料技术与工程研究所 | 2024-12-27 | — | — | CN | disclosed |
| CN-117567846-A | Polyester composition and articles thereof | 长春人造树脂厂股份有限公司 | 2024-02-20 | — | — | CN | disclosed |
| CN-116059409-A | Novel technetium-99 m therapeutic diagnostic agent for cardiac radiography and ventricular evaluation and evaluation method | 程毓渡 | 2023-05-05 | — | — | CN | disclosed |
| CN-115084646-A | Cyclotriphosphazene-based flame-retardant polymer electrolyte and preparation method and application thereof | 江西师范大学 | 2022-09-20 | — | — | CN | disclosed |
| EP-2118247-B2 | IMPROVED METHOD FOR RECOVERING OIL FROM PLANT SEEDS | AB ENZYMES GMBH (DE) | 2022-05-11 | — | — | EP | disclosed |
| CN-108475822-B | Nonaqueous electrolyte solution for secondary battery and secondary battery provided with same | 斯泰拉化工公司 | 2022-03-11 | — | — | CN | disclosed |
| EP-0822189-A2 | Method for producing purified epoxy compound | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1998-02-04 | — | — | EP | disclosed |
| EP-0371721-B1 | Preparation process for aromatic hydroxycarboxylic acid | MITSUI TOATSU CHEMICALS (JP) | 1994-07-27 | — | — | EP | disclosed |
| CN-1069051-A | The cold light pipe of a kind of chemical luminous system and system thereof | DALIAN CHEMICAL PHYSICS INST (CN) | 1993-02-17 | — | — | CN | disclosed |
| US-4950781-A | REACTING AN ALKALI METAL MALT OF PHENOL WITH CARBON DI OXIDE IN PRESENCE OF PHOSPHINE OXIDE SOLVENT | MITSUI TOATSU CHEMICALS, INC. (JP) | 1990-08-21 | — | — | US | disclosed |
| EP-0371721-A2 | Preparation process for aromatic hydroxycarboxylic acid | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1990-06-06 | — | — | EP | disclosed |
| US-4827027-A | Separation/purification of salicyclic acid | RHONE-POULENC SPECIALITES CHIMIQUES (FR) | 1989-05-02 | — | — | US | disclosed |
| US-4681950-A | PHOTOSENSITIZERS | CIBA-GEIGY CORPORATION (US) | 1987-07-21 | — | — | US | disclosed |
| US-4585876-A | PHOTOSENSITIZERS | CIBA-GEIGY CORPORATION (US) | 1986-04-29 | — | — | US | disclosed |
| US-4176075-A | Dioxime and hydroxy benzoic acid metal salt antioxidants for lithium soap grease compositions | EXXON RESEARCH & ENGINEERING CO. (US) | 1979-11-27 | — | — | US | disclosed |