Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Salicylic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 1.00 |
| ▸ | HPGD | P15428 | 5/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | CA2 | P00918 | 2/20 | 0.58 |
| ▸ | CA4 | P22748 | 2/20 | 0.58 |
| ▸ | CA1 | P00915 | 2/20 | 0.58 |
| ▸ | CA9 | Q16790 | 2/20 | 0.58 |
| ▸ | CA12 | O43570 | 1/20 | 0.58 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.58 |
| ▸ | CA6 | P23280 | 1/20 | 0.58 |
| ▸ | CA7 | P43166 | 1/20 | 0.58 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.58 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | MPO | P05164 | 1/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Salicylic Acid SCHEMBL16116234 | 1.00 | KDM4E (1.00) | KDM4EHPGDALDH1A1SMN1; SMN2CA2 | |
| Salicylic Acid SCHEMBL10793800 | 1.00 | KDM4E (1.00) | KDM4EHPGDALDH1A1SMN1; SMN2CA2 | |
| Salicylic Acid SCHEMBL28341718 | 1.00 | KDM4E (1.00) | KDM4EHPGDALDH1A1SMN1; SMN2CA2 | |
| Salicylic Acid SCHEMBL455422 | 1.00 | KDM4E (1.00) | KDM4EHPGDALDH1A1SMN1; SMN2CA2 | |
| Salicylic Acid SCHEMBL29888959 | 1.00 | KDM4E (1.00) | KDM4EHPGDALDH1A1SMN1; SMN2CA2 | |
| Salicylic Acid SCHEMBL10708399 | 0.98 | KDM4E (0.95) | KDM4EHPGDALDH1A1SMN1; SMN2CA2 | |
| Salicylic Acid SCHEMBL3312655 | 0.98 | KDM4E (0.95) | KDM4EHPGDALDH1A1SMN1; SMN2CA2 | |
| Salicylic Acid SCHEMBL5450889 | 0.98 | KDM4E (0.95) | KDM4EHPGDALDH1A1SMN1; SMN2CA2 | |
| Salicylic Acid SCHEMBL8683263 | 0.98 | KDM4E (0.95) | KDM4EHPGDALDH1A1SMN1; SMN2CA2 | |
| Salicylic Acid SCHEMBL31668375 | 0.98 | KDM4E (0.95) | KDM4EHPGDALDH1A1SMN1; SMN2CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 45616 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4009987-B1 | LIQUID DRESSING COMPOSITIONS COMPRISING SHELLAC AND METALS | CAMBRIDGE ENTPR LTD (GB) | 2026-05-27 | — | — | EP | claimed |
| CN-122075375-A | Liquid crystal composition and application thereof | — | 2026-05-26 | — | — | CN | claimed |
| US-12638605-B2 | Plasma light detection system including a scintillating window | SAMSUNG ELECTRONICS CO. LTD. (KR) | 2026-05-26 | — | — | US | claimed |
| CN-122070813-A | Copper doped nano magnesium hydroxide, preparation method and application | 浙江新安化工集团股份有限公司 | 2026-05-22 | — | — | CN | claimed |
| EP-4009988-B1 | LIQUID DRESSING COMPOSITIONS COMPRISING SHELLAC AND METALS FOR VETERINARY USES | CAMBRIDGE ENTPR LTD (GB) | 2026-05-20 | — | — | EP | claimed |
| EP-4744680-A1 | TARGETED CHEMICAL DRUG AND PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION, AND USE OF TARGETED CHEMICAL DRUG | Bai Yao Zhi Da (Beijing) Nanobio Technology Co., Ltd. (CN) | 2026-05-20 | — | — | EP | claimed |
| CN-122060426-A | Modified hydrotalcite ultraviolet inhibitor with dual energy dissipation mechanism and application thereof in photovoltaic encapsulation | 山东大学 | 2026-05-19 | — | — | CN | claimed |
| CN-121796660-B | Postoperative drainage abdomen pad and preparation method thereof | 金士达医疗（咸宁）有限公司 | 2026-05-19 | — | — | CN | claimed |
| CN-122059599-A | Harmless treatment process for oil sludge wastewater | 浙江美宝工业科技股份有限公司 | 2026-05-19 | — | — | CN | claimed |
| CN-122057064-A | Multifunctional composite hemostatic powder capable of achieving wound in-situ self-gelation and preparation method thereof | 杨鑫 | 2026-05-19 | — | — | CN | claimed |
| US-4036227-A | Osmotic releasing device having a plurality of release rate patterns | ALZA CORPORATION (US) | 1977-07-19 | — | — | US | claimed |
| US-4036228-A | Osmotic dispenser with gas generating means | ALZA CORPORATION (US) | 1977-07-19 | — | — | US | claimed |
| US-4015130-A | Method and apparatus for monitoring optical radiation | THE UNITED STATES OF AMERICA (US) | 1977-03-29 | — | — | US | claimed |
| US-4003989-A | SODIUM SALICYLATE OR ACETYLSALICYLIC ACID; WATER SOLUBILITY | RAFA LABORATORIES LTD. (IL) | 1977-01-18 | — | — | US | claimed |
| US-3997470-A | POTASSIUM FERRICYANIDE AND CYANIDE, SODIUM BICARBONATE, MANNITOL | MALLINCKRODT, INC. (US) | 1976-12-14 | — | — | US | claimed |
| US-3997598-A | CARBOXYLATE OR PHOSPHORIC ACID, CRYSTALLIZATION | HOECHST AKTIENGESELLSCHAFT (DT) | 1976-12-14 | — | — | US | claimed |
| US-3990978-A | ALUMINUM SALT OF PHOSPHATE ESTER | THE DOW CHEMICAL COMPANY (US) | 1976-11-09 | — | — | US | claimed |
| US-3973967-A | PRINTING PLATES, RESOLUTION | ITEK CORPORATION (US) | 1976-08-10 | — | — | US | claimed |
| US-3964255-A | Method of inflating an automobile passenger restraint bag | SPECIALTY PRODUCTS DEVELOPMENT CORPORATION (US) | 1976-06-22 | — | — | US | claimed |
| US-3949072-A | PHENOLATE, SALICYLATE, RESORCINOL, ZINC COMPOUND | TENTA LOUIS T | 1976-04-06 | — | — | US | claimed |