Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | FAAH | O00519 | 1/20 | 0.52 |
| ▸ | PHGDH | O43175 | 1/20 | 0.52 |
| ▸ | MGLL | Q99685 | 1/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6788749 | 0.97 | KMT2A (0.52) | KMT2APOLBKDM4EFAAHPHGDH | |
| Bromomethane SCHEMBL11185005 | 0.95 | KMT2A (0.50) | KMT2APOLBKDM4EFAAHPHGDH | |
| Carbamic Acid SCHEMBL11482908 | 0.93 | KMT2A (0.48) | KMT2APOLBKDM4EFAAHPHGDH | |
| Acetonitrile SCHEMBL11793629 | 0.89 | KMT2A (0.46) | KMT2APOLBKDM4EFAAHPHGDH | |
| Ethyne SCHEMBL27564823 | 0.89 | KDM4E (0.46) | KMT2APOLBKDM4EFAAHPHGDH | |
| Benzophenone SCHEMBL28515512 | 0.89 | HPGD (0.62) | KMT2APOLBKDM4ELMNAL3MBTL1 | |
| SCHEMBL1730118 | 0.86 | ALDH1A1 (0.48) | KDM4ERAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL17704773 | 0.84 | KMT2A (0.53) | KMT2APOLBKDM4EFAAHPHGDH | |
| SCHEMBL320116 | 0.84 | POLB (0.59) | KMT2APOLBKDM4EFAAHPHGDH | |
| SCHEMBL208445 | 0.82 | ALDH1A1 (0.54) | KMT2APOLBKDM4EFAAHPHGDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 369 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240279207-A1 | SUBSTITUTED ACYL SULFONAMIDES FOR TREATING CANCER | BAYER AKTIENGESELLSCHAFT (DE) | 2024-08-22 | — | — | US | claimed |
| CN-118239868-A | Carbamate substituted styryl sulfone compound and preparation method and application thereof | 华夏生生药业(北京)有限公司 | 2024-06-25 | — | — | CN | claimed |
| EP-4001263-B1 | CARBAMATE-SUBSTITUTED STYRYL SULFONE COMPOUND, PREPARATION METHOD, AND APPLICATION THEREOF | HUAXIASHENGSHENG PHARMACEUTICAL BEIJING CO LTD (CN) | 2024-03-27 | — | — | EP | claimed |
| EP-4001263-A1 | CARBAMATE-SUBSTITUTED STYRYL SULFONE COMPOUND, PREPARATION METHOD, AND APPLICATION THEREOF | Huaxiashengsheng Pharmaceutical Beijing Co., Ltd. (CN) | 2022-05-25 | — | — | EP | claimed |
| CN-114072380-A | Carbamate substituted styryl sulfone compound and preparation method and application thereof | 华夏生生药业(北京)有限公司 | 2022-02-18 | — | — | CN | claimed |
| EP-2592934-B1 | NOVEL DIHYDROPYRIDIN-2(1H)-ONE COMPOUNDS AS S-NITROSOGLUTATHIONE REDUCTASE INHIBITORS AND NEUROKININ-3 RECEPTOR ANTAGONISTS | NIVALIS THERAPEUTICS INC (US) | 2015-08-26 | — | — | EP | claimed |
| EP-2562171-B1 | GERMINATION-STIMULANT CARBAMATE DERIVATIVES AND PROCESS FOR PREPARATION THEREOF | NAT UNIV CORP UNIV KOBE (JP) | 2015-01-21 | — | — | EP | claimed |
| EP-2616169-A2 | CHROMATOGRAPHY MEMBRANES FOR THE PURIFICATION OF CHIRAL COMPOUNDS | Natrix Separations Inc. (CA) | 2013-07-24 | — | — | EP | claimed |
| US-8431572-B2 | 2-oxo-3-benzylbenzoxazol-2-one derivatives and related compounds as met kinase inhibitors for the treatment of tumours | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2013-04-30 | — | — | US | claimed |
| EP-1879877-B1 | ANTIMICROBIAL AGENTS | RANBAXY LAB LTD (IN) | 2013-01-02 | — | — | EP | claimed |
| EP-0016441-B1 | A METHOD FOR THE PREPARATION OF A MIXTURE OF DIPHENYL METHANE DICARBAMATES AND POLYMETHYLENE POLYPHENYL CARBAMATES | ATLANTIC RICHFIELD COMPANY (US) | 1982-05-12 | — | — | EP | claimed |
| US-4320113-A | Process for controlling cockroaches and other crawling insects | HERCULITE PROTECTIVE FABRICS CORPORATION (US) | 1982-03-16 | — | — | US | claimed |
| EP-0014482-B1 | PREPARATION OF DIPHENYLMETHANE DICARBAMATES AND POLYMETHYLENE POLYPHENYL CARBAMATES WITH LEWIS ACID CATALYSTS INTERCALATED IN GRAPHITE | ATLANTIC RICHFIELD COMPANY (US) | 1981-11-25 | — | — | EP | claimed |
| US-4289693-A | TEXTILES | SANDOZ LTD. (CH) | 1981-09-15 | — | — | US | claimed |
| EP-0027330-A1 | Process for the production of methylenedicarbanilates and the compounds thus obtained | MITSUBISHI KASEI CORPORATION (JP) | 1981-04-22 | — | — | EP | claimed |
| US-4230877-A | ACID CATALYZED CONDENSATION OF AN N-ARYL CARBAMIC ACID ESTER WITH A CARBONYL COMPOUND | ATLANTIC RICHFIELD COMPANY (US) | 1980-10-28 | — | — | US | claimed |
| EP-0016441-A2 | A method for the preparation of a mixture of diphenyl methane dicarbamates and polymethylene polyphenyl carbamates | ATLANTIC RICHFIELD COMPANY (US) | 1980-10-01 | — | — | EP | claimed |
| EP-0014482-A1 | Preparation of diphenylmethane dicarbamates and polymethylene polyphenyl carbamates with Lewis acid catalysts intercalated in graphite | ATLANTIC RICHFIELD COMPANY (US) | 1980-08-20 | — | — | EP | claimed |
| US-4202986-A | Preparation of diphenylmethane dicarbamates and polymethylene polyphenyl carbamates with Lewis acid catalysts intercalated in graphite | ATLANTIC RICHFIELD COMPANY (US) | 1980-05-13 | — | — | US | claimed |
| US-4162362-A | CONDESATION OF N-ARYL CARBAMIC ACID ESTER WITH FORMALDEHYDE IN THE PRESENCE OF A SULFONIC ACID | ATLANTIC RICHFIELD COMPANY (US) | 1979-07-24 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240279207-A1 | SUBSTITUTED ACYL SULFONAMIDES FOR TREATING CANCER | KAT6A, KAT6B, KAT2A | KMT2A 23/4885POLB 566/4885KDM4E 383/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.