Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 4/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4553074 | 0.84 | — | — | |
| SCHEMBL4554753 | 0.83 | HTR2A (0.35) | — | |
| SCHEMBL963161 | 0.76 | IRAK4 (0.32) | IRAK4 | |
| SCHEMBL963547 | 0.73 | SMN1; SMN2 (0.41) | IRAK4 | |
| SCHEMBL4555113 | 0.70 | MEN1 (0.35) | IRAK4 | |
| SCHEMBL962959 | 0.70 | HPGD (0.32) | IRAK4 | |
| SCHEMBL967739 | 0.70 | IRAK4 (0.35) | IRAK4 | |
| SCHEMBL967741 | 0.70 | IRAK4 (0.35) | IRAK4 | |
| SCHEMBL4553736 | 0.69 | HTR2A (0.34) | — | |
| SCHEMBL27772808 | 0.69 | FGFR1 (0.40) | IRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2118066-A1 | FUSED RING COMPOUNDS AS PARTIAL AGONISTS OF PPAR-GAMMA | Takeda Pharmaceutical Company Limited (JP) | 2009-11-18 | — | — | EP | disclosed |
| WO-2008099794-A1 | FUSED RING COMPOUNDS AS PARTIAL AGONISTS OF PPAR-GAMMA | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-08-21 | — | — | WO | disclosed |