Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 19/20 | 0.60 |
| ▸ | NR1H3 | Q13133 | 4/20 | 0.55 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5713778 | 0.83 | NR1H2 (0.57) | NR1H2NR1H3CA12CA9 | |
| SCHEMBL30711377 | 0.83 | NR1H2 (0.57) | NR1H2NR1H3CA12CA9 | |
| SCHEMBL17022654 | 0.83 | NR1H2 (0.57) | NR1H2NR1H3CA12CA9 | |
| SCHEMBL28615203 | 0.83 | L3MBTL1 (0.47) | NR1H2NR1H3 | |
| SCHEMBL5599682 | 0.82 | NR1H2 (0.56) | NR1H2NR1H3CA12CA9 | |
| SCHEMBL29942670 | 0.82 | NR1H2 (0.56) | NR1H2NR1H3CA12CA9 | |
| SCHEMBL28370689 | 0.82 | NR1H2 (0.56) | NR1H2NR1H3CA12CA9 | |
| SCHEMBL4125402 | 0.82 | NR1H2 (0.60) | NR1H2NR1H3CA12CA9 | |
| SCHEMBL7913537 | 0.82 | NR1H2 (0.56) | NR1H2NR1H3CA12CA9 | |
| SCHEMBL17422843 | 0.82 | NR1H2 (0.56) | NR1H2NR1H3CA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107835814-A | Azabenzimidazoles and their use as ampa receptor modulators | 詹森药业有限公司 | 2018-03-23 | — | — | CN | disclosed |
| EP-2114454-A2 | CHEMICAL LINKERS AND CLEAVABLE SUBSTRATES AND CONJUGATES THEREOF | Medarex, Inc. (US) | 2009-11-11 | — | — | EP | disclosed |
| WO-2008083312-A2 | CHEMICAL LINKERS AND CLEAVABLE SUBSTRATES AND CONJUGATES THEREOF | MEDAREX, INC. (US) | 2008-07-10 | — | — | WO | disclosed |