Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 20/20 | 0.54 |
| ▸ | PGR | P06401 | 7/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | NR3C2 | P08235 | 13/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4553625 | 0.93 | NR3C1 (0.49) | NR3C1PGRCYP3A4NR3C2 | |
| SCHEMBL6668738 | 0.88 | NR3C1 (0.47) | NR3C1PGRNR3C2 | |
| SCHEMBL4447862 | 0.83 | NR3C1 (0.71) | NR3C1PGRCYP3A4NR3C2 | |
| SCHEMBL4556027 | 0.82 | NR3C1 (0.54) | NR3C1PGRCYP3A4NR3C2 | |
| SCHEMBL3688034 | 0.81 | NR3C1 (0.67) | NR3C1PGRNR3C2 | |
| SCHEMBL291973 | 0.80 | NR3C1 (0.80) | NR3C1PGRCYP3A4NR3C2 | |
| SCHEMBL3689474 | 0.79 | NR3C1 (0.65) | NR3C1PGRCYP3A4NR3C2 | |
| SCHEMBL4556423 | 0.79 | NR3C1 (0.52) | NR3C1PGRNR3C2 | |
| SCHEMBL451275 | 0.76 | NR3C1 (0.56) | NR3C1PGRNR3C2 | |
| SCHEMBL3650787 | 0.76 | NR3C1 (0.64) | NR3C1PGRCYP3A4NR3C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012170175-A1 | COMPOSITIONS AND METHODS FOR TREATING, CONTROLLING, REDUCING, OR AMELIORATING INFLAMMATORY PAIN | BAUSCH & LOMB INCORPORATED (US) | 2012-12-13 | — | — | WO | disclosed |
| EP-2061444-A2 | COMPOSITIONS AND METHODS FOR TREATING, CONTROLLING, REDUCING, AMELIORATING, OR PREVENTING ALLERGY | Bausch & Lomb Incorporated (US) | 2009-05-27 | — | — | EP | disclosed |
| WO-2008033655-A2 | COMPOSITIONS AND METHODS FOR TREATING, CONTROLLING, REDUCING, AMELIORATING, OR PREVENTING ALLERGY | BAUSCH & LOMB INCORPORATED (US) | 2008-03-20 | — | — | WO | disclosed |