Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 11/20 | 0.38 |
| ▸ | CA1 | P00915 | 9/20 | 0.38 |
| ▸ | CA5A | P35218 | 7/20 | 0.38 |
| ▸ | CA5B | Q9Y2D0 | 7/20 | 0.38 |
| ▸ | CA9 | Q16790 | 6/20 | 0.38 |
| ▸ | CA12 | O43570 | 5/20 | 0.38 |
| ▸ | CA3 | P07451 | 2/20 | 0.38 |
| ▸ | CA4 | P22748 | 2/20 | 0.38 |
| ▸ | CA6 | P23280 | 2/20 | 0.38 |
| ▸ | CA7 | P43166 | 2/20 | 0.38 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 8/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3737819 | 0.86 | CA2 (0.54) | CA2CA1CA5ACA5BCA9 | |
| SCHEMBL4554833 | 0.83 | CA2 (0.39) | CA2CA1CA5ACA5BCA9 | |
| Bromide SCHEMBL4555224 | 0.82 | CA2 (0.42) | CA2CA1CA5ACA5BCA9 | |
| Bromide SCHEMBL4555222 | 0.82 | CA2 (0.42) | CA2CA1CA5ACA5BCA9 | |
| SCHEMBL3737820 | 0.69 | CA2 (0.56) | CA2CA1CA5ACA5BCA9 | |
| SCHEMBL3737816 | 0.69 | CA2 (0.56) | CA2CA1CA5ACA5BCA9 | |
| SCHEMBL13012320 | 0.68 | CA2 (0.62) | CA2CA1CA5ACA5BCA9 | |
| Bromide SCHEMBL3738018 | 0.67 | CA2 (0.61) | CA2CA1CA5ACA5BCA9 | |
| Bromide SCHEMBL3738017 | 0.67 | CA2 (0.61) | CA2CA1CA5ACA5BCA9 | |
| SCHEMBL16975062 | 0.66 | CA2 (0.52) | CA2CA1CA5ACA5BCA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2129666-A2 | DEVELOPMENT OF MOLECULAR IMAGING PROBES FOR CARBONIC ANHYDRASE-IX USING CLICK CHEMISTRY | Siemens Medical Solutions USA, Inc. (US) | 2009-12-09 | — | — | EP | disclosed |
| WO-2008124703-A2 | DEVELOPMENT OF MOLECULAR IMAGING PROBES FOR CARBONIC ANHYDRASE-IX USING CLICK CHEMISTRY | SIEMENS MEDICAL SOLUTIONS USA, INC. (US) | 2008-10-16 | — | — | WO | disclosed |