Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.31 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.31 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL967727 | 0.88 | GABRA1 (0.33) | GABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL967726 | 0.88 | GABRA1 (0.33) | GABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL4555074 | 0.85 | GABRA1 (0.32) | GABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL961971 | 0.80 | FFAR1 (0.35) | — | |
| SCHEMBL961973 | 0.80 | FFAR1 (0.35) | — | |
| SCHEMBL966023 | 0.70 | PPARG (0.38) | — | |
| SCHEMBL966024 | 0.70 | PPARG (0.38) | — | |
| SCHEMBL965655 | 0.70 | NPY5R (0.33) | — | |
| SCHEMBL965653 | 0.70 | NPY5R (0.33) | — | |
| SCHEMBL966085 | 0.69 | SMN1; SMN2 (0.41) | GABRA1GABRG2GABRB3GABRA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2118066-A1 | FUSED RING COMPOUNDS AS PARTIAL AGONISTS OF PPAR-GAMMA | Takeda Pharmaceutical Company Limited (JP) | 2009-11-18 | — | — | EP | disclosed |
| WO-2008099794-A1 | FUSED RING COMPOUNDS AS PARTIAL AGONISTS OF PPAR-GAMMA | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-08-21 | — | — | WO | disclosed |