Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | WDR5 | P61964 | 3/20 | 0.31 |
| ▸ | F10 | P00742 | 5/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4440841 | 0.92 | MAOA (0.48) | MAOBMAOACYP2C19WDR5F10 | |
| SCHEMBL9968647 | 0.91 | MAOB (0.40) | MAOBMAOACYP2C19WDR5F10 | |
| SCHEMBL4555118 | 0.87 | MAOA (0.39) | MAOBMAOACYP2C19WDR5F10 | |
| SCHEMBL9930507 | 0.85 | MAOA (0.32) | MAOBMAOACYP2C19 | |
| SCHEMBL4553635 | 0.82 | MAOA (0.38) | MAOBMAOAKCNH2 | |
| SCHEMBL14069388 | 0.82 | MAOA (0.38) | MAOBMAOAKCNH2 | |
| SCHEMBL9964860 | 0.80 | MAOA (0.47) | MAOBMAOACYP2C19WDR5F10 | |
| SCHEMBL9930041 | 0.79 | MAOB (0.47) | MAOBMAOACYP2C19WDR5KCNH2 | |
| SCHEMBL9929866 | 0.79 | MAOA (0.40) | MAOBMAOACYP2C19WDR5 | |
| SCHEMBL9930226 | 0.79 | MAOB (0.47) | MAOBMAOACYP2C19WDR5KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2134721-A1 | ANTIMICROBIAL HETEROCYCLIC COMPOUNDS FOR TREATMENT OF BACTERIAL INFECTIONS | Micurx Pharmaceuticals, Inc. (US) | 2009-12-23 | — | — | EP | disclosed |
| WO-2008108988-A1 | ANTIMICROBIAL HETEROCYCLIC COMPOUNDS FOR TREATMENT OF BACTERIAL INFECTIONS | MICURX PHARMACEUTICALS, INC. (US) | 2008-09-12 | — | — | WO | disclosed |