SCHEMBL455532

SCHEMBL455532

FC(F)(F)c1[c]cc(C(F)(F)F)c(C(F)(F)F)c1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3432402 0.74
SCHEMBL147906 0.73
SCHEMBL8778382 0.72
SCHEMBL15063687 0.68 NOTUM (0.30)
SCHEMBL6754916 0.67 POLB (0.41)
SCHEMBL9902343 0.67
SCHEMBL145308 0.66 ALDH1A1 (0.35)
SCHEMBL9902673 0.66 GLA (0.31)
SCHEMBL457917 0.65 CYP1A2 (0.33)
SCHEMBL28895821 0.64 NT5E (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4394981-A1 NONAQUEOUS ELECTROLYTE AND NONAQUEOUS ELECTROLYTE SECONDARY BATTERY SHIN-ETSU CHEMICAL CO., LTD. (JP) 2024-07-03 EP disclosed
EP-4006040-A1 PYRROMETHENE-BORON COMPLEX, COLOR CONVERSION COMPOSITION, COLOR CONVERSION FILM, LIGHT SOURCE UNIT, DISPLAY, AND LIGHTING DEVICE Toray Industries, Inc. (JP) 2022-06-01 EP disclosed
US-20210061821-A1 PYRROMETHENE BORON COMPLEX, COLOR CONVERSION COMPOSITION, COLOR CONVERSION FILM, LIGHT SOURCE UNIT, DISPLAY, ILLUMINATION APPARATUS, AND LIGHT-EMITTING DEVICE TORAY INDUSTRIES, INC. (JP) 2021-03-04 US disclosed
US-10907094-B2 Pyrromethene-boron complex, color conversion composition, color conversion film, light source unit, display, and illumination apparatus TORAY INDUSTRIES, INC. (JP) 2021-02-02 US disclosed
US-20190345380-A1 PYRROMETHENE-BORON COMPLEX, COLOR CONVERSION COMPOSITION, COLOR CONVERSION FILM, LIGHT SOURCE UNIT, DISPLAY, AND ILLUMINATION APPARATUS TORAY INDUSTRIES, INC. (JP) 2019-11-14 US disclosed
EP-3550206-A1 PYRROMETHENE-BORON COMPLEX, COLOR CONVERSION COMPOSITION, COLOR CONVERSION FILM, LIGHT SOURCE UNIT, DISPLAY, AND ILLUMINATION DEVICE Toray Industries, Inc. (JP) 2019-10-09 EP disclosed
CN-109996802-A Methylene pyrrole boron complex, color shifting combination object, color conversion film, light source unit, display and lighting device 东丽株式会社 2019-07-09 CN disclosed
EP-3045450-B1 INTERMEDIATE COMPOUNDS IN PROCESSES FOR PRODUCING PYRIDAZINONE COMPOUNDS SUMITOMO CHEMICAL CO (JP) 2018-02-07 EP disclosed
CN-104277004-B Prepare method and its intermediate of pyridazinone compound 住友化学株式会社 2016-08-24 CN disclosed
CN-104326952-B Prepare method and its intermediate of pyridazinone compound 住友化学株式会社 2016-08-24 CN disclosed
US-20040214853-A1 Naphthyridine derivatives OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) 2004-10-28 US disclosed
EP-1426374-A1 NAPHTHYRIDINE DERIVATIVE OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) 2004-06-09 EP disclosed
US-6706905-B1 REACTING AROMATIC COMPOUND, PALLADIUM(II) COMPOUND, AND PHOSPHINE DERIVATIVE; COMPLEXING WITH BENZOIC ACID DERIVATIVE; METALLIZATION CENTRAL GLASS COMPANY, LIMITED (JP) 2004-03-16 US disclosed
US-6448247-B1 TACHYKININ RECEPTOR ANTAGONIST; ESPECIALLY TO THE RECEPTORS FOR SUBSTANCE P (WHICH RECEPTORS ARE GENERALLY REFERRED TO AS ?NEUROKININ 1 RECEPTORS?) SANKYO COMPANY, LIMITED (JP) 2002-09-10 US disclosed
US-6353009-B1 TREATMENT OF GOUT WITH ANTIINFLAMMATORY AGENTS SANKYO COMPANY, LIMITED (JP) 2002-03-05 US disclosed
EP-0776893-B1 Azaheterocyclic compounds having tachykinin receptor antagonist activity; Nk1 and NK2 SANKYO CO (JP) 2002-02-27 EP disclosed
US-6159967-A Heterocyclic compounds having tachykinin receptor antagonist activity their preparation and their use SANKYO COMPANY, LIMITED (JP) 2000-12-12 US disclosed
EP-1008601-A2 Method for producing palladium complex compound Central Glass Company, Limited (JP) 2000-06-14 EP disclosed
EP-0919232-A1 Composition for use in the treatment and prevention of hyperuricemia Sankyo Company Limited (JP) 1999-06-02 EP disclosed
EP-0776893-A1 Azaheterocyclic compounds having tachykinin receptor antagonist activity; Nk1 and NK2 SANKYO COMPANY LIMITED (JP) 1997-06-04 EP disclosed