Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.60 |
| ▸ | MEN1 | O00255 | 6/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | BRPF1 | P55201 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | BRD4 | O60885 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | NR0B1 | P51843 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4555552 | 0.86 | SMN1; SMN2 (0.57) | SMN1; SMN2MEN1KMT2AATMRAB9A | |
| SCHEMBL2815071 | 0.84 | MEN1 (0.54) | SMN1; SMN2MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL2816819 | 0.84 | MEN1 (0.63) | SMN1; SMN2MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL2814955 | 0.83 | ALDH1A1 (0.65) | SMN1; SMN2MEN1KMT2AATMRAB9A | |
| SCHEMBL4555548 | 0.82 | SMN1; SMN2 (0.59) | SMN1; SMN2MEN1KMT2AATMRAB9A | |
| SCHEMBL2813712 | 0.82 | KMT2A (0.67) | SMN1; SMN2MEN1KMT2ARAB9AL3MBTL1 | |
| SCHEMBL2819556 | 0.82 | MEN1 (0.56) | SMN1; SMN2MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL2815527 | 0.82 | MEN1 (0.56) | SMN1; SMN2MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL4554813 | 0.81 | NPC1 (0.51) | SMN1; SMN2MEN1KMT2ARAB9ATSHR | |
| SCHEMBL2846912 | 0.81 | MAPT (0.52) | SMN1; SMN2MEN1KMT2ARAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2134676-A2 | NOVEL BENZAMIDE DERIVATIVES AS MODULATORS OF THE FOLLICLE STIMULATING HORMONE | Addex Pharma SA (CH) | 2009-12-23 | — | — | EP | claimed |
| WO-2008117175-A2 | NOVEL BENZAMIDE DERIVATIVES AS MODULATORS OF THE FOLLICLE STIMULATING HORMONE | ADDEX PHARMA SA (CH) | 2008-10-02 | — | — | WO | claimed |