Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | CES1 | P23141 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30039450 | 0.78 | MEN1 (0.49) | ALDH1A1MEN1KMT2AGAAPOLB | |
| SCHEMBL21034823 | 0.78 | MEN1 (0.49) | ALDH1A1MEN1KMT2AGAAPOLB | |
| SCHEMBL983366 | 0.76 | HDAC4 (0.42) | HDAC4KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL12922380 | 0.76 | HDAC4 (0.42) | HDAC4KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL983365 | 0.76 | HDAC4 (0.42) | HDAC4KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL4441712 | 0.76 | HDAC4 (0.50) | HDAC4KDM4EALDH1A1PDK2KMT2A | |
| SCHEMBL4555610 | 0.75 | HDAC4 (0.62) | HDAC4ALDH1A1PDK2GAA | |
| SCHEMBL30038630 | 0.74 | MEN1 (0.48) | HDAC4ALDH1A1MEN1KMT2AGAA | |
| SCHEMBL21034067 | 0.74 | MEN1 (0.48) | HDAC4ALDH1A1MEN1KMT2AGAA | |
| SCHEMBL29661878 | 0.73 | HDAC4 (0.60) | HDAC4PDK2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2134692-A2 | QUINOLINE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM FOR SELECTIN INHIBITION | Wyeth a Corporation of the State of Delaware (US) | 2009-12-23 | — | — | EP | disclosed |
| WO-2008121817-A2 | QUINOLINE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM FOR SELECTIN INHIBITION | WYETH (US) | 2008-10-09 | — | — | WO | disclosed |