Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 11/20 | 0.63 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.45 |
| ▸ | CLK2 | P49760 | 1/20 | 0.45 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.45 |
| ▸ | SRPK1 | Q96SB4 | 1/20 | 0.45 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.45 |
| ▸ | DDR2 | Q16832 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CASP6 | P55212 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2815607 | 0.85 | POLB (0.54) | KDM4ENPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL4555964 | 0.81 | MAOB (0.46) | MAOBMAOAMAP4K4CLK2DYRK1A | |
| SCHEMBL2818030 | 0.75 | NTRK1 (0.52) | MAOBKDM4ENPC1RAB9ALMNA | |
| SCHEMBL2815379 | 0.75 | POLB (0.54) | KDM4ENPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL2817492 | 0.75 | POLB (0.54) | KDM4ENPC1RAB9ALMNASMN1; SMN2 | |
| SCHEMBL27796995 | 0.74 | MAOB (0.60) | MAOBMAOAMAP4K4CLK2DYRK1A | |
| SCHEMBL2816711 | 0.73 | NPC1 (0.53) | KDM4ENPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL15764659 | 0.72 | NPC1 (0.74) | MAOBMAOAMAP4K4CLK2DYRK1A | |
| SCHEMBL2820320 | 0.72 | LMNA (0.57) | NPC1RAB9ALMNAMEN1ALDH1A1 | |
| SCHEMBL15887019 | 0.72 | MAOB (0.84) | MAOBMAOAMAP4K4CLK2DYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2134676-A2 | NOVEL BENZAMIDE DERIVATIVES AS MODULATORS OF THE FOLLICLE STIMULATING HORMONE | Addex Pharma SA (CH) | 2009-12-23 | — | — | EP | disclosed |
| WO-2008117175-A2 | NOVEL BENZAMIDE DERIVATIVES AS MODULATORS OF THE FOLLICLE STIMULATING HORMONE | ADDEX PHARMA SA (CH) | 2008-10-02 | — | — | WO | disclosed |