Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 14/20 | 0.81 |
| ▸ | RHOC | P08134 | 6/20 | 0.56 |
| ▸ | RHOA | P61586 | 6/20 | 0.56 |
| ▸ | TACR3 | P29371 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8300981 | 1.00 | TACR1 (0.81) | TACR1RHOCRHOATACR3 | |
| SCHEMBL3203637 | 1.00 | TACR1 (0.81) | TACR1RHOCRHOATACR3 | |
| SCHEMBL8291732 | 1.00 | TACR1 (0.81) | TACR1RHOCRHOATACR3 | |
| SCHEMBL8297226 | 0.89 | TACR1 (1.00) | TACR1RHOCRHOATACR3 | |
| SCHEMBL7459083 | 0.89 | TACR1 (1.00) | TACR1RHOCRHOATACR3 | |
| SCHEMBL8499946 | 0.88 | TACR1 (0.62) | TACR1RHOCRHOATACR3 | |
| SCHEMBL8296860 | 0.86 | TACR1 (0.75) | TACR1RHOCRHOATACR3 | |
| SCHEMBL7614360 | 0.85 | TACR1 (0.71) | TACR1RHOCRHOATACR3 | |
| SCHEMBL7614357 | 0.85 | TACR1 (0.71) | TACR1RHOCRHOATACR3 | |
| SCHEMBL8500550 | 0.85 | TACR1 (0.71) | TACR1RHOCRHOATACR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2124949-A1 | PHARMACEUTICAL FORMULATION | Avera Pharmaceuticals, Inc. (US) | 2009-12-02 | — | — | EP | disclosed |
| WO-2008103914-A1 | PHARMACEUTICAL FORMULATION | AVERA PHARMACEUTICALS, INC. (US) | 2008-08-28 | — | — | WO | disclosed |
| US-5935951-A | ANTAGONIST AGAINST SUBSTANCE P | NOVARTIS FINANCE CORPORATION (US) | 1999-08-10 | — | — | US | disclosed |