Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | NQO2 | P16083 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4555913 | 0.88 | SMN1; SMN2 (0.42) | KMT2AMEN1KDM4EMAPTALDH1A1 | |
| SCHEMBL7460001 | 0.86 | ABCG2 (0.40) | ABCG2KMT2AMEN1MAPTNQO2 | |
| SCHEMBL7712878 | 0.84 | LMNA (0.40) | ABCG2KMT2AMEN1MAPTNQO2 | |
| SCHEMBL2942736 | 0.82 | CHRM2 (0.47) | ABCG2KMT2AMEN1KDM4EMAPT | |
| SCHEMBL4447689 | 0.78 | MAPT (0.39) | ABCG2KMT2AMEN1MAPTNPC1 | |
| SCHEMBL4556803 | 0.78 | PIM1 (0.37) | KMT2AMEN1KDM4EMAPTNPC1 | |
| SCHEMBL2918502 | 0.76 | NQO2 (0.45) | ABCG2KMT2AMEN1MAPTNQO2 | |
| SCHEMBL4556158 | 0.75 | MEN1 (0.44) | ABCG2KMT2AMEN1MAPTNQO2 | |
| SCHEMBL2914961 | 0.73 | CHRM2 (0.53) | ABCG2KMT2AMEN1KDM4EMAPT | |
| SCHEMBL2921015 | 0.73 | TOP2A (0.47) | ABCG2KMT2AMEN1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7622478-B2 | 1-nitroacridine/tumor inhibitor compositions | TIWARI RAJ | 2009-11-24 | — | — | US | claimed |