Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | MMP1 | P03956 | 1/20 | 0.45 |
| ▸ | MMP2 | P08253 | 1/20 | 0.45 |
| ▸ | MMP9 | P14780 | 1/20 | 0.45 |
| ▸ | MMP8 | P22894 | 1/20 | 0.45 |
| ▸ | MMP13 | P45452 | 1/20 | 0.45 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.45 |
| ▸ | CA5A | P35218 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL425911 | 0.90 | TSHR (0.59) | LMNATSHRGAAHTTKMT2A | |
| SCHEMBL8331382 | 0.88 | TSHR (0.48) | LMNATSHRGAAHTTKMT2A | |
| SCHEMBL2903776 | 0.86 | KMT2A (0.54) | LMNATSHRGAAHTTKMT2A | |
| SCHEMBL7583669 | 0.85 | TSHR (0.53) | LMNATSHRGAAHTTKMT2A | |
| SCHEMBL143162 | 0.85 | TSHR (0.67) | LMNATSHRGAAHTTKMT2A | |
| SCHEMBL29601516 | 0.85 | TSHR (0.67) | LMNATSHRGAAHTTKMT2A | |
| SCHEMBL8825063 | 0.84 | TSHR (0.52) | LMNATSHRGAAHTTKMT2A | |
| SCHEMBL5421317 | 0.83 | KMT2A (0.58) | LMNATSHRGAAHTTKMT2A | |
| SCHEMBL31145718 | 0.83 | TSHR (0.64) | LMNATSHRGAAHTTKMT2A | |
| Bromide SCHEMBL31058252 | 0.83 | TSHR (0.64) | LMNATSHRGAAHTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090234072-A1 | CURABLE COMPOSITION | KANEKA CORPORATION (JP) | 2009-09-17 | — | — | US | disclosed |
| EP-1923431-A1 | CURABLE COMPOSITION | Kaneka Corporation (JP) | 2008-05-21 | — | — | EP | disclosed |