Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL306614 | 0.85 | P2RX7 (0.33) | P2RX7 | |
| SCHEMBL4556544 | 0.79 | P2RX7 (0.47) | P2RX7 | |
| SCHEMBL307034 | 0.77 | P2RX7 (0.33) | P2RX7 | |
| SCHEMBL308133 | 0.68 | P2RX7 (0.46) | P2RX7 | |
| SCHEMBL306895 | 0.68 | P2RX7 (0.46) | P2RX7 | |
| SCHEMBL307485 | 0.68 | P2RX7 (0.46) | P2RX7 | |
| SCHEMBL305933 | 0.66 | P2RX7 (0.36) | P2RX7 | |
| SCHEMBL306217 | 0.64 | P2RX7 (0.34) | P2RX7 | |
| SCHEMBL8140694 | 0.64 | P2RX7 (0.38) | P2RX7 | |
| SCHEMBL4438657 | 0.63 | P2RX7 (0.46) | P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2124562-A1 | BICYCLOHETEROARYL COMPOUNDS AS P2X7 MODULATORS AND USES THEREOF | Renovis, Inc. (US) | 2009-12-02 | — | — | EP | disclosed |
| WO-2008112205-A1 | BICYCLOHETEROARYL COMPOUNDS AS P2X7 MODULATORS AND USES THEREOF | RENOVIS, INC. (US) | 2008-09-18 | — | — | WO | disclosed |