Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC7 | O00311 | 1/20 | 0.31 |
| ▸ | PLK4 | O00444 | 1/20 | 0.31 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.31 |
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.31 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.31 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.31 |
| ▸ | INSR | P06213 | 1/20 | 0.31 |
| ▸ | CDK1 | P06493 | 1/20 | 0.31 |
| ▸ | ROS1 | P08922 | 1/20 | 0.31 |
| ▸ | PIM1 | P11309 | 1/20 | 0.31 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.31 |
| ▸ | PRKACA | P17612 | 1/20 | 0.31 |
| ▸ | FLT1 | P17948 | 1/20 | 0.31 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.31 |
| ▸ | CDK2 | P24941 | 1/20 | 0.31 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.31 |
| ▸ | FLT4 | P35916 | 1/20 | 0.31 |
| ▸ | KDR | P35968 | 1/20 | 0.31 |
| ▸ | FLT3 | P36888 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3153398 | 0.88 | EPHX2 (0.39) | CDC7PLK4DYRK3JAK2ROCK2 | |
| SCHEMBL4556459 | 0.83 | NPSR1 (0.33) | RECQLUSP2 | |
| SCHEMBL4564569 | 0.82 | JAK3 (0.39) | JAK2RPS6KB1AURKBCYP2C9PLAU | |
| SCHEMBL3149479 | 0.80 | EPHX2 (0.39) | DYRK1A | |
| SCHEMBL3144720 | 0.76 | HDAC1 (0.39) | DYRK1AGAAKMT2ACYP2C19USP2 | |
| SCHEMBL3153349 | 0.72 | NAMPT (0.40) | USP2 | |
| SCHEMBL3144560 | 0.71 | NAMPT (0.40) | RECQLUSP2ALDH1A1PLAU | |
| SCHEMBL3149495 | 0.69 | NAMPT (0.40) | RPS6KB1USP2 | |
| SCHEMBL3144699 | 0.69 | NAMPT (0.39) | RPS6KB1 | |
| SCHEMBL3139295 | 0.69 | EPHX2 (0.46) | JAK2GAACYP2C9CYP2C19ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009133348-A1 | AMINOPYRIDINE DERIVATIVES | VANTIA LIMITED (GB) | 2009-11-05 | — | — | WO | disclosed |