Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 19/20 | 1.00 |
| ▸ | PTGES | O14684 | 11/20 | 1.00 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.62 |
| ▸ | GAA | P10253 | 1/20 | 0.62 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL530099 | 0.88 | ALOX5 (1.00) | ALOX5PTGES | |
| SCHEMBL4325014 | 0.88 | ALOX5 (1.00) | ALOX5PTGESMEN1ALDH1A1CYP1A2 | |
| SCHEMBL4338584 | 0.87 | ALOX5 (1.00) | ALOX5PTGESMEN1ALDH1A1CYP1A2 | |
| SCHEMBL4558769 | 0.83 | ALOX5 (1.00) | ALOX5PTGESMEN1ALDH1A1CYP1A2 | |
| SCHEMBL4558554 | 0.83 | ALOX5 (1.00) | ALOX5PTGES | |
| SCHEMBL4332344 | 0.78 | ALOX5 (1.00) | ALOX5PTGES | |
| SCHEMBL4558273 | 0.77 | ALOX5 (0.87) | ALOX5PTGES | |
| SCHEMBL4326672 | 0.77 | ALOX5 (1.00) | ALOX5PTGES | |
| SCHEMBL4558098 | 0.76 | ALOX5 (0.79) | ALOX5PTGES | |
| SCHEMBL4558036 | 0.75 | ALOX5 (0.77) | ALOX5PTGES |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009146696-A1 | USE OF INDOLE-3-CARBOXYLIC ESTERS FOR INHIBITING MICROSOMAL PROSTAGLANDIN E2 SYNTHASE | Universität Tübingen (DE) | 2009-12-10 | — | — | WO | disclosed |