Methane

Methane

SCHEMBL4556718

C.CC(C(=O)O)c1cc(C(C)(C)C)c(O)c(C(C)(C)C)c1

nearest known ligand 0.48

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GLRA3 O75311 1/20 0.48
GLRB P48167 1/20 0.48
CA2 P00918 3/20 0.47
CA1 P00915 2/20 0.47
ALDH1A1 P00352 2/20 0.45
SMN1; SMN2 Q16637 2/20 0.45
POLB P06746 1/20 0.45
TYR P14679 1/20 0.45
GAA P10253 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
GABBR2 O75899 2/20 0.44
GABBR1 Q9UBS5 2/20 0.44
GPR55 Q9Y2T6 1/20 0.42
MEN1 O00255 1/20 0.42
GALR3 O60755 1/20 0.42
HTT P42858 1/20 0.42
KMT2A Q03164 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
CYP1A2 P05177 1/20 0.41
CYP2D6 P10635 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6275312 0.98 GLRA3 (0.50) GLRA3GLRBCA2CA1ALDH1A1
SCHEMBL100584 0.98 GLRA3 (0.50) GLRA3GLRBCA2CA1ALDH1A1
Charcoal, Activated SCHEMBL30758836 0.96 GLRA3 (0.48) GLRA3GLRBCA2CA1ALDH1A1
SCHEMBL27309992 0.96 GLRA3 (0.48) GLRA3GLRBCA2CA1ALDH1A1
Hydrochloric Acid SCHEMBL1874072 0.96 GLRA3 (0.48) GLRA3GLRBCA2CA1ALDH1A1
Hydrogen Sulfide SCHEMBL27550937 0.96 GLRA3 (0.48) GLRA3GLRBCA2CA1ALDH1A1
SCHEMBL38652274 0.96 GLRA3 (0.48) GLRA3GLRBCA2CA1ALDH1A1
Hydrazine SCHEMBL28264032 0.95 GLRA3 (0.47) GLRA3GLRBCA2CA1ALDH1A1
Hydrazine SCHEMBL27641524 0.95 GLRA3 (0.47) GLRA3GLRBCA2CA1ALDH1A1
Maleic Acid SCHEMBL11741118 0.90 GABBR2 (0.46) GLRA3GLRBCA2CA1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111032351-B Composition for preparing recyclable polycarbonate sheet having matte appearance 盛禧奥欧洲有限责任公司 2021-07-13 CN disclosed
CN-102300888-B Bulk Polymerization Of Silicone-containing Copolymers 3M INNOVATIVE PROPERTIES CO 2014-09-17 CN disclosed
CN-102417611-B Stabilizer compositions CYTEC TECH CORP 2014-07-02 CN disclosed
CN-102417611-A Stabilizer compositions CYTEC TECH CORP 2012-04-18 CN disclosed
CN-102300888-A Bulk Polymerization Of Silicone-containing Copolymers 2011-12-28 CN disclosed
CN-101448888-B stabilizer composition CYTEC TECH CORP 2011-10-05 CN disclosed
EP-1384752-B1 INSULATED ELECTRIC WIRE YAZAKI CORP (JP) 2009-10-28 EP disclosed
CN-101448888-A stabilizer composition CYTEC TECH CORP (US) 2009-06-03 CN disclosed
US-6894227-B2 Insulated electric wire YAZAKI CORPORATION (JP) 2005-05-17 US disclosed
US-20040168820-A1 INSULATED ELECTRIC WIRE YAZAKI CORPORATION (JP) 2004-09-02 US disclosed
EP-0346862-B1 Process to graft stereoregular polymers of branched, higher alpha-olefins and compositions thereof PHILLIPS PETROLEUM CO (US) 1995-10-25 EP disclosed
EP-0556843-A1 Polyolefins with improved toughness and high clarity PHILLIPS PETROLEUM COMPANY (US) 1993-08-25 EP disclosed
EP-0346862-A2 Process to graft stereoregular polymers of branched, higher alpha-olefins and compositions thereof PHILLIPS PETROLEUM COMPANY (US) 1989-12-20 EP disclosed
US-4888394-A HEAT RESISTANCE, HYDROLYTIC STABILITY PHILLIPS PETROLEUM COMPANY (US) 1989-12-19 US disclosed
EP-0110573-B1 POLYAMIDE COMPOSITIONS RAYCHEM CORPORATION (a California corporation) (US) 1987-09-23 EP disclosed
EP-0110573-A1 Polyamide compositions RAYCHEM CORPORATION (a California corporation) (US) 1984-06-13 EP disclosed