Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 9/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1310474 | 0.87 | MEN1 (0.45) | MEN1KMT2AALDH1A1MAPTLMNA | |
| SCHEMBL1161503 | 0.82 | CYP1A2 (0.42) | MEN1KMT2AALDH1A1LMNAPOLB | |
| SCHEMBL17611774 | 0.81 | MEN1 (0.42) | MEN1KMT2AALDH1A1MAPTLMNA | |
| SCHEMBL390461 | 0.81 | USP2 (0.42) | MEN1KMT2AALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL1141219 | 0.81 | CYP1A2 (0.41) | ALDH1A1LMNAPOLBOPRM1OPRD1 | |
| SCHEMBL17611768 | 0.80 | MEN1 (0.42) | MEN1KMT2AALDH1A1MAPTLMNA | |
| SCHEMBL4551724 | 0.80 | OPRM1 (0.42) | MEN1KMT2AALDH1A1POLBOPRM1 | |
| SCHEMBL425037 | 0.79 | SMN1; SMN2 (0.41) | MEN1KMT2AALDH1A1LMNARAB9A | |
| SCHEMBL2079 | 0.79 | CYP1A2 (0.39) | MEN1KMT2AALDH1A1LMNARAB9A | |
| SCHEMBL1447297 | 0.79 | KMT2A (0.46) | MEN1KMT2AALDH1A1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2125820-A1 | SUBSTITUTED PIPERIDINES CONTAINING A HETEROARYLAMIDE OR HETEROARYLPHENYL MOIETY | Astex Therapeutics Limited (GB) | 2009-12-02 | — | — | EP | disclosed |
| WO-2008075110-A1 | SUBSTITUTED PIPERIDINES CONTAINING A HETEROARYLAMIDE OR HETEROARYLPHENYL MOIETY | ASTEX THERAPEUTICS LIMITED (GB) | 2008-06-26 | — | — | WO | disclosed |