Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | TSPO | P30536 | 1/20 | 0.52 |
| ▸ | MGLL | Q99685 | 1/20 | 0.51 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.48 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.48 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22560026 | 0.85 | LMNA (0.62) | LMNAALDH1A1TSHRMAPK1NPSR1 | |
| SCHEMBL965307 | 0.84 | LMNA (0.66) | LMNAALDH1A1TSHRMAPK1NPSR1 | |
| SCHEMBL965736 | 0.83 | LMNA (0.64) | LMNAALDH1A1TSHRMAPK1NPSR1 | |
| SCHEMBL1195514 | 0.81 | LMNA (0.78) | LMNAALDH1A1TSHRMAPK1NPSR1 | |
| SCHEMBL15270613 | 0.81 | EPHX2 (0.46) | LMNAHDAC1HDAC6NPC1MEN1 | |
| SCHEMBL967320 | 0.80 | LMNA (0.70) | LMNAALDH1A1TSHRMAPK1NPSR1 | |
| SCHEMBL10777744 | 0.80 | LMNA (0.60) | LMNAALDH1A1TSHRMAPK1NPSR1 | |
| Hydrochloric Acid SCHEMBL27708825 | 0.79 | LMNA (0.68) | LMNAALDH1A1TSHRMAPK1TSPO | |
| SCHEMBL4188820 | 0.79 | NPC1 (0.65) | ALDH1A1NPC1MEN1KMT2ARAB9A | |
| SCHEMBL9547626 | 0.78 | LMNA (0.92) | LMNAALDH1A1TSHRMAPK1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009145360-A1 | BENZENE OR THIOPHENE DERIVATIVE AND USE THEREOF AS VAP-1 INHIBITOR | R-TECH UENO, LTD. (JP) | 2009-12-03 | — | — | WO | claimed |