Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 7/20 | 0.41 |
| ▸ | NR3C1 | P04150 | 6/20 | 0.41 |
| ▸ | PGR | P06401 | 5/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MLNR | O43193 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.41 |
| ▸ | SHBG | P04278 | 4/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6334150 | 0.90 | AR (0.43) | ARLMNANR3C1PGRCYP3A4 | |
| SCHEMBL30295174 | 0.85 | LMNA (0.38) | ARLMNANR3C1PGRCYP3A4 | |
| SCHEMBL26133329 | 0.80 | LMNA (0.51) | ARLMNANR3C1PGRCYP3A4 | |
| SCHEMBL5697443 | 0.80 | LMNA (0.51) | ARLMNANR3C1PGRCYP3A4 | |
| SCHEMBL11119294 | 0.80 | AR (0.55) | ARLMNANR3C1PGRCYP3A4 | |
| SCHEMBL30295200 | 0.79 | LMNA (0.36) | ARLMNANR3C1PGRCYP3A4 | |
| SCHEMBL30295226 | 0.79 | LMNA (0.36) | ARLMNANR3C1PGRCYP3A4 | |
| SCHEMBL30295268 | 0.79 | LMNA (0.36) | ARLMNANR3C1PGRCYP3A4 | |
| SCHEMBL4557359 | 0.78 | AR (0.47) | ARLMNANR3C1PGRCYP3A4 | |
| SCHEMBL4557358 | 0.78 | AR (0.47) | ARLMNANR3C1PGRCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2026818-A2 | COMBINATION OF ANTI-INFLAMMATORY STEROIDS HAVING TRANSPORTER-ENHANCED CORTICOSTEROID ACTIVITY | Bodor, Nicholas S. (US) | 2009-02-25 | — | — | EP | disclosed |
| WO-2007142842-A2 | COMBINATION OF ANTI-INFLAMMATORY STEROIDS HAVING TRANSPORTER-ENHANCED CORTICOSTEROID ACTIVITY | BODOR NICHOLAS S (US) | 2007-12-13 | — | — | WO | disclosed |