Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10448860 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL2880388 | 0.62 | — | — | |
| SCHEMBL2879089 | 0.62 | — | — | |
| Hydrochloric Acid SCHEMBL11825950 | 0.61 | TSHR (0.30) | — | |
| SCHEMBL902747 | 0.60 | TSHR (0.33) | — | |
| Hydrochloric Acid SCHEMBL8004082 | 0.60 | — | — | |
| SCHEMBL1688001 | 0.58 | — | — | |
| Vinyl Chloride SCHEMBL4449125 | 0.57 | — | — | |
| SCHEMBL1460960 | 0.56 | — | — | |
| SCHEMBL4790574 | 0.56 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8981079-B2 | Purification of tertiary formamide contaminated with tertiary acetamide | TATE & LYLE TECHNOLOGY LIMITED (GB) | 2015-03-17 | — | — | US | disclosed |
| US-20120157675-A1 | PURIFICATION OF TERTIARY FORMAMIDE CONTAMINATED WITH TERTIARY ACETAMIDE | TATE & LYLE TECHNOLOGY LIMITED (GB) | 2012-06-21 | — | — | US | disclosed |
| US-20090131653-A1 | Generation of Phosphorus Oxychloride as by-Product from Phosphorus Pentachloride and DMF and its Use for Chlorination Reaction by Converting Into Vilsmeier-Haack Reagent | PHARMED MEDICARE PRIVATE LIMITED (IN) | 2009-05-21 | — | — | US | disclosed |
| US-20090030193-A1 | Synthesis of Vilsmeier Haack Reagent from Di(Trichlo-Romethyl) Carbonate for Chlorination Reaction | PHARMED MEDICARE PRIVATE LIMITED (IN) | 2009-01-29 | — | — | US | disclosed |
| US-20080300392-A1 | Novel chlorination process for preparing sucralose | POLYMED THERAPEUTICS, INC. (US) | 2008-12-04 | — | — | US | disclosed |
| US-20080300401-A1 | Novel chlorination process for preparing sucralose | POLYMED THERAPEUTICS, INC. (US) | 2008-12-04 | — | — | US | disclosed |
| EP-1888611-A2 | GENERATION OF PHOSPHORUS OXYCHLORIDE AS BY-PRODUCT FROM PHOSPHORUS PENTACHLORIDE AND DMF AND ITS USE FOR CHLORINATION REACTION BY CONVERTING INTO VILSMEIER-HAACK REAGENT. | Pharmed Medicare Private Limited (IN) | 2008-02-20 | — | — | EP | disclosed |
| WO-2007017891-A2 | GENERATION OF PHOSPHORUS OXYCHLORIDE AS BY-PRODUCT FROM PHOSPHORUS PENTACHLORIDE AND DMF AND ITS USE FOR CHLORINATION REACTION BY CONVERTING INTO VILSMEIER-HAACK REAGENT. | PHARMED MEDICARE PRIVATE LIMITED (IN) | 2007-02-15 | — | — | WO | disclosed |
| WO-2006072965-A2 | SUCROSE-6-ESTER CHLORINATION BY CO-ADDITION OF CHLORINATION REAGENT. | PHARMED MEDICARE PRIVATE LIMITED (IN) | 2006-07-13 | — | — | WO | disclosed |
| EP-0260979-B1 | SUCROSE DERIVATIVES | TATE & LYLE PUBLIC LIMITED COMPANY (GB) | 1991-05-15 | — | — | EP | disclosed |
| EP-0103479-A1 | Sucrose derivatives | TATE & LYLE PUBLIC LIMITED COMPANY (GB) | 1984-03-21 | — | — | EP | disclosed |
| EP-0050952-B1 | SWEET CHLORINE-SUBSTITUTED DISACCHARIDES | TATE & LYLE PUBLIC LIMITED COMPANY (GB) | 1983-09-21 | — | — | EP | disclosed |
| US-4405654-A | 4'-Halo-substituted sucrose derivatives | TATE & LYLE PUBLIC LIMITED COMPANY (GB) | 1983-09-20 | — | — | US | disclosed |
| US-4380476-A | Process for the preparation of 4,1',6'-trichloro-4,1',6'-trideoxygalactosucrose (TGS) | TALRES DEVELOPMENT (N.A.) N.V. (AN) | 1983-04-19 | — | — | US | disclosed |
| EP-0031651-B1 | PROCESS FOR THE PREPARATION OF 4,1',6'-TRICHLORO-4,1',6'-TRIDEOXY-GALACTOSUCROSE | TATE & LYLE PUBLIC LIMITED COMPANY (GB) | 1983-03-23 | — | — | EP | disclosed |
| EP-0073093-A1 | 4' Halo-substituted sucrose derivatives | TATE & LYLE PUBLIC LIMITED COMPANY (GB) | 1983-03-02 | — | — | EP | disclosed |
| US-4362869-A | Process for the preparation of 4,1',6'-trichloro-4,1',6'-trideoxygalactosucrose | TALRES DEVELOPMENT (N.A.) N.V. (AN) | 1982-12-07 | — | — | US | disclosed |
| EP-0050952-A1 | Sweet chlorine-substituted disaccharides | TATE & LYLE PUBLIC LIMITED COMPANY (GB) | 1982-05-05 | — | — | EP | disclosed |
| EP-0043649-A1 | Process for the preparation of 4, 1',6'-trichloro-4,1',6'-trideoxygalactosucrose (TGS) | TATE & LYLE PUBLIC LIMITED COMPANY (GB) | 1982-01-13 | — | — | EP | disclosed |
| EP-0031651-A1 | Process for the preparation of 4,1',6'-trichloro-4,1',6'-trideoxy-galactosucrose | TATE & LYLE PUBLIC LIMITED COMPANY (GB) | 1981-07-08 | — | — | EP | disclosed |