Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3917392 | 0.77 | PTPN1 (0.41) | PTPN1PTPN2 | |
| Potassium SCHEMBL3917394 | 0.77 | PTPN1 (0.41) | PTPN1PTPN2 | |
| SCHEMBL4782763 | 0.77 | PTPN1 (0.46) | PTPN1PTPN2 | |
| SCHEMBL4733377 | 0.75 | PTPN1 (0.51) | PTPN1PTPN2 | |
| SCHEMBL2933873 | 0.75 | PTPN1 (0.48) | PTPN1PTPN2 | |
| SCHEMBL2937456 | 0.73 | PTPN1 (0.48) | PTPN1PTPN2 | |
| SCHEMBL3215930 | 0.73 | PTPN1 (0.56) | PTPN1PTPN2 | |
| SCHEMBL3213657 | 0.72 | PTPN1 (0.45) | PTPN1PTPN2 | |
| SCHEMBL27758423 | 0.72 | KDM4E (0.32) | — | |
| SCHEMBL4461683 | 0.72 | PTPN1 (0.44) | PTPN1PTPN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2089026-A2 | INHIBITORS OF PROTEIN TYROSINE PHOSPHATASE FOR THE PROMOTION OF PHYSIOLOGICAL CARDIAC HYPERTROPHY | Novartis AG (CH) | 2009-08-19 | — | — | EP | disclosed |
| WO-2008070552-A2 | INHIBITORS OF PROTEIN TYROSINE PHOSPHATASE FOR THE PROMOTION OF PHYSIOLOGICAL CARDIAC HYPERTROPHY | NOVARTIS AG (CH) | 2008-06-12 | — | — | WO | disclosed |