Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 11/20 | 0.51 |
| ▸ | PTPN2 | P17706 | 12/20 | 0.33 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3208657 | 0.91 | PTPN1 (0.58) | PTPN1PTPN2AMY1A | |
| SCHEMBL4557565 | 0.87 | PTPN1 (0.44) | PTPN1PTPN2 | |
| SCHEMBL3916808 | 0.83 | PTPN1 (0.55) | PTPN1PTPN2 | |
| SCHEMBL2935550 | 0.82 | PTPN1 (0.55) | PTPN1PTPN2 | |
| SCHEMBL647600 | 0.81 | PTPN1 (0.56) | PTPN1PTPN2 | |
| SCHEMBL647669 | 0.81 | PTPN1 (0.56) | PTPN1PTPN2 | |
| SCHEMBL648815 | 0.80 | PTPN1 (0.53) | PTPN1PTPN2 | |
| SCHEMBL2935548 | 0.80 | PTPN1 (0.53) | PTPN1PTPN2 | |
| SCHEMBL4782763 | 0.79 | PTPN1 (0.46) | PTPN1PTPN2 | |
| SCHEMBL4785652 | 0.79 | PTPN1 (0.56) | PTPN1PTPN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008067527-A1 | INHIBITORS OF PROTEIN TYROSINE PHOSPHATASE FOR THE TREATMENT OF MUSCLE ATROPHY AND RELATED DISORDERS | NOVARTIS AG (CH) | 2008-06-05 | — | — | WO | disclosed |