Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 15/20 | 0.45 |
| ▸ | TRPV4 | Q9HBA0 | 2/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.36 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13930468 | 0.80 | DRD2 (0.41) | GRM5 | |
| SCHEMBL13930056 | 0.78 | GRM5 (0.38) | GRM5 | |
| SCHEMBL13930599 | 0.76 | GRM5 (0.37) | GRM5 | |
| SCHEMBL14206772 | 0.72 | GRM5 (0.43) | GRM5 | |
| SCHEMBL3832517 | 0.71 | POLB (0.44) | GRM5 | |
| SCHEMBL3832527 | 0.70 | SCD (0.42) | — | |
| SCHEMBL3826339 | 0.70 | SCD (0.41) | — | |
| SCHEMBL13930469 | 0.68 | DRD2 (0.38) | GRM5 | |
| SCHEMBL14130918 | 0.67 | GRM5 (0.40) | GRM5 | |
| SCHEMBL13930607 | 0.66 | GRM5 (0.36) | GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009037542-A2 | SPIROCYCLIC COMPOUNDS AS STEAROYL COA DESATURASE INHIBITORS | GLENMARK PHARMACEUTICALS, S.A. (US) | 2009-03-26 | — | — | WO | claimed |
| WO-2009037542-A2 | SPIROCYCLIC COMPOUNDS AS STEAROYL COA DESATURASE INHIBITORS | GLENMARK PHARMACEUTICALS, S.A. (US) | 2009-03-26 | — | — | WO | disclosed |