Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | SYK | P43405 | 15/20 | 0.47 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3265212 | 0.85 | SYK (0.49) | MAPTSYKTAS2R14PKM | |
| SCHEMBL12411198 | 0.81 | IDH1 (0.47) | GAAMAPTSYKTAS2R14PKM | |
| SCHEMBL13965269 | 0.78 | IDH1 (0.53) | GAAMAPTSYKTAS2R14PKM | |
| SCHEMBL2141628 | 0.77 | SYK (0.49) | SYKTAS2R14PKM | |
| SCHEMBL8000248 | 0.76 | IDH1 (0.53) | SYKTAS2R14 | |
| SCHEMBL8350149 | 0.76 | PKM (0.52) | GAAMAPTSYKTAS2R14PKM | |
| SCHEMBL14310598 | 0.76 | PKM (0.59) | GAAMAPTSYKTAS2R14PKM | |
| SCHEMBL12932877 | 0.74 | HRH4 (0.50) | GAAMAPTSYKPKM | |
| SCHEMBL30636648 | 0.74 | SYK (0.62) | GAASYKTAS2R14 | |
| SCHEMBL12963477 | 0.74 | PKM (0.57) | GAAMAPTSYKTAS2R14PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130289013-A1 | IMIDAZO[1,2-a]PYRIDINE COMPOUNDS | SUNOVION PHARMACEUTICALS INC. | 2013-10-31 | — | — | US | disclosed |
| WO-2012052412-A1 | NOVEL HETEROCYCLIC COMPOUNDS AS PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2012-04-26 | — | — | WO | disclosed |
| US-20110166146-A1 | IMIDAZO[1,2-a]PYRIDINE COMPOUNDS | SUNOVION PHARMACEUTICALS INC. (US) | 2011-07-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110166146-A1 | IMIDAZO[1,2-a]PYRIDINE COMPOUNDS | PAICS, ITPA, DPYD | GAA 218/4885MAPT 2245/4885SYK 3487/4885 |
| US-20130289013-A1 | IMIDAZO[1,2-a]PYRIDINE COMPOUNDS | PAICS, ITPA, DPYD | GAA 218/4885MAPT 2245/4885SYK 3487/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.