Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.53 |
| ▸ | MEN1 | O00255 | 7/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.53 |
| ▸ | HPGD | P15428 | 5/20 | 0.53 |
| ▸ | MAPT | P10636 | 5/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | PKM | P14618 | 2/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | PHGDH | O43175 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4328939 | 1.00 | KMT2A (0.53) | KMT2AMEN1ALDH1A1HPGDMAPT | |
| SCHEMBL4326576 | 0.83 | SMN1; SMN2 (0.39) | KMT2AMEN1ALDH1A1HPGDMAPT | |
| SCHEMBL4455856 | 0.82 | KMT2A (0.60) | KMT2AMEN1ALDH1A1HPGDMAPT | |
| SCHEMBL4341232 | 0.81 | KMT2A (0.58) | KMT2AMEN1ALDH1A1HPGDMAPT | |
| SCHEMBL4333822 | 0.80 | ALDH1A1 (0.50) | KMT2AMEN1ALDH1A1HPGDMAPT | |
| SCHEMBL4331665 | 0.80 | KMT2A (0.56) | KMT2AMEN1ALDH1A1HPGDMAPT | |
| SCHEMBL4331661 | 0.80 | KMT2A (0.56) | KMT2AMEN1ALDH1A1HPGDMAPT | |
| SCHEMBL13887398 | 0.78 | KMT2A (0.57) | KMT2AMEN1ALDH1A1HPGDMAPT | |
| SCHEMBL6445038 | 0.77 | KMT2A (0.63) | KMT2AMEN1ALDH1A1HPGDMAPT | |
| SCHEMBL4453437 | 0.77 | KMT2A (0.63) | KMT2AMEN1ALDH1A1HPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7521062-B2 | Thiosemicarbazones as anti-virals and immunopotentiators | NOVARTIS VACCINES & DIAGNOSTICS, INC. (US) | 2009-04-21 | — | — | US | disclosed |