Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.44 |
| ▸ | POLB | P06746 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 7/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | MITF | O75030 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.43 |
| ▸ | AGTR1 | P30556 | 3/20 | 0.42 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.41 |
| ▸ | MEN1 | O00255 | 7/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 2/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4557465 | 0.81 | CDK5 (0.37) | MAPTPOLBLMNAHPGDNPSR1 | |
| SCHEMBL2919819 | 0.74 | NUDT1 (0.43) | MAPTLMNAHPGDNPSR1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7519436 | 0.72 | MAPT (0.47) | MAPTPOLBLMNAHPGDNPSR1 | |
| SCHEMBL7199031 | 0.70 | PIM1 (0.42) | MAPTLMNASMN1; SMN2HTTL3MBTL1 | |
| SCHEMBL7717111 | 0.68 | KDM4E (0.47) | MAPTPOLBLMNAHPGDNPSR1 | |
| SCHEMBL7643951 | 0.65 | PIM1 (0.42) | MAPTPOLBLMNAHPGDSMN1; SMN2 | |
| SCHEMBL13436799 | 0.64 | MAPT (0.70) | MAPTPOLBLMNAHPGDNPSR1 | |
| SCHEMBL28785698 | 0.63 | MAPT (0.46) | MAPTPOLBLMNAHPGDNPSR1 | |
| SCHEMBL2915128 | 0.62 | CHRM2 (0.48) | MAPTPOLBLMNAHPGDNPSR1 | |
| Hydrochloric Acid SCHEMBL7519432 | 0.62 | KMT2A (0.36) | MAPTPOLBLMNASMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7622478-B2 | 1-nitroacridine/tumor inhibitor compositions | TIWARI RAJ | 2009-11-24 | — | — | US | claimed |