Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 12/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 4/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 4/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 4/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 4/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 4/20 | 0.33 |
| ▸ | CHRNA1 | P02708 | 3/20 | 0.33 |
| ▸ | CHRNG | P07510 | 3/20 | 0.33 |
| ▸ | CHRNB1 | P11230 | 3/20 | 0.33 |
| ▸ | CHRND | Q07001 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | THPO | P40225 | 1/20 | 0.33 |
| ▸ | CHRNE | Q04844 | 1/20 | 0.33 |
| ▸ | CHRNA2 | Q15822 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL454467 | 0.69 | CYP1A2 (0.68) | CYP1A2SIGMAR1 | |
| SCHEMBL10579794 | 0.69 | CYP1A2 (0.68) | CYP1A2SIGMAR1 | |
| SCHEMBL11503388 | 0.69 | CYP1A2 (0.68) | CYP1A2SIGMAR1 | |
| SCHEMBL4969658 | 0.69 | CYP1A2 (0.68) | CYP1A2SIGMAR1 | |
| SCHEMBL8080519 | 0.67 | CYP1A2 (0.65) | CYP1A2SIGMAR1 | |
| SCHEMBL9190697 | 0.65 | SIGMAR1 (0.70) | CYP1A2SIGMAR1 | |
| SCHEMBL11653901 | 0.65 | SIGMAR1 (0.70) | CYP1A2SIGMAR1 | |
| SCHEMBL8023611 | 0.65 | SIGMAR1 (0.70) | CYP1A2SIGMAR1 | |
| SCHEMBL5614191 | 0.65 | SIGMAR1 (0.70) | CYP1A2SIGMAR1 | |
| SCHEMBL1207447 | 0.65 | CYP1A2 (0.60) | CYP1A2SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7622526-B2 | Thermoset material based on antiplasticizing polythiourethane and ophthalmic lens comprising an antiplasticized thermoset material | ESSILOR INTERNATIONAL (FR) | 2009-11-24 | — | — | US | disclosed |
| US-20060270771-A1 | Thermoset material based on antiplasticizing polythiourethane and ophthalmic lens comprising an antiplasticized thermoset material | ESSILOR INTERNATIONAL COMPAGNIE GENERALE D'OPTIQUE (FR) | 2006-11-30 | — | — | US | disclosed |