Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4557999 | 0.89 | CCKBR (0.82) | CCKBRCCKAR | |
| SCHEMBL4494479 | 0.83 | CCKBR (0.50) | CCKBRCCKAR | |
| SCHEMBL3913222 | 0.80 | CCKBR (1.00) | CCKBRCCKAR | |
| SCHEMBL4500797 | 0.78 | CCKBR (0.82) | CCKBRCCKAR | |
| SCHEMBL4505102 | 0.78 | CCKBR (0.63) | CCKBRCCKAR | |
| SCHEMBL13868249 | 0.77 | CCKBR (0.74) | CCKBRCCKAR | |
| SCHEMBL13868362 | 0.77 | CCKBR (0.91) | CCKBRCCKAR | |
| SCHEMBL5449645 | 0.76 | CCKBR (0.84) | CCKBRCCKAR | |
| SCHEMBL4505312 | 0.76 | CCKBR (0.52) | CCKBRCCKAR | |
| SCHEMBL5812109 | 0.75 | CCKBR (0.47) | CCKBRCCKAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1948624-B1 | PROCESS FOR THE PREPARATION OF BENZO[E][1,2,4]TRIAZEPIN-2-ONE DERIVATIVES | JANSSEN PHARMACEUTICA NV (BE) | 2013-10-23 | — | — | EP | disclosed |
| US-7582753-B2 | Process for the preparation of benzotriazepine derivatives | JANSSENPHARMACEUTICA, NV (BE) | 2009-09-01 | — | — | US | disclosed |
| US-20070066819-A1 | PROCESS FOR THE PREPARATION OF BENZOTRIAZEPINE DERIVATIVES | JANSSEN PHARMACUETICA N.V., (BE) | 2007-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070066819-A1 | PROCESS FOR THE PREPARATION OF BENZOTRIAZEPINE DERIVATIVES | CCKBR, CCKAR, GRPR | CCKBR 1/4885CCKAR 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.