Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLG | P00747 | 17/20 | 0.43 |
| ▸ | PLAU | P00749 | 17/20 | 0.43 |
| ▸ | F10 | P00742 | 7/20 | 0.43 |
| ▸ | ST14 | Q9Y5Y6 | 6/20 | 0.43 |
| ▸ | F2 | P00734 | 5/20 | 0.43 |
| ▸ | HPN | P05981 | 2/20 | 0.39 |
| ▸ | HGFAC | Q04756 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4557533 | 0.89 | PLG (0.48) | PLGPLAUF10ST14F2 | |
| Hydrochloric Acid SCHEMBL4458403 | 0.88 | PLG (0.47) | PLGPLAUF10ST14F2 | |
| SCHEMBL2953288 | 0.76 | PLAU (0.48) | PLGPLAUF10ST14F2 | |
| Hydrochloric Acid SCHEMBL4451933 | 0.75 | PLAU (0.48) | PLGPLAUF10ST14F2 | |
| SCHEMBL2954061 | 0.67 | PLAU (0.52) | PLGPLAUF10ST14F2 | |
| Hydrochloric Acid SCHEMBL250043 | 0.66 | PLAU (0.51) | PLGPLAUF10ST14F2 | |
| SCHEMBL4619934 | 0.63 | PLAU (0.44) | PLGPLAUF10ST14F2 | |
| SCHEMBL6129266 | 0.62 | PLAU (0.61) | PLGPLAUF10ST14F2 | |
| SCHEMBL2265830 | 0.59 | SLC7A5 (0.53) | — | |
| SCHEMBL31329363 | 0.59 | SLC7A5 (0.53) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1511721-B1 | GUANIDINO PHENYLALANIN COMPOUNDS USED AS UROKINASE INHIBITORS | WILEX AG (DE) | 2009-07-01 | — | — | EP | disclosed |