Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 19/20 | 0.61 |
| ▸ | PLG | P00747 | 18/20 | 0.61 |
| ▸ | F10 | P00742 | 7/20 | 0.61 |
| ▸ | F2 | P00734 | 6/20 | 0.61 |
| ▸ | ST14 | Q9Y5Y6 | 6/20 | 0.61 |
| ▸ | HPN | P05981 | 2/20 | 0.54 |
| ▸ | HGFAC | Q04756 | 1/20 | 0.54 |
| ▸ | PLAT | P00750 | 2/20 | 0.53 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.53 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| N-(Ethoxycarbonyl)Piperazine SCHEMBL2874625 | 0.81 | PLAU (0.80) | PLAUPLGF10F2ST14 | |
| N-(Ethoxycarbonyl)Piperazine SCHEMBL4606324 | 0.81 | PLAU (0.80) | PLAUPLGF10F2ST14 | |
| N-(Ethoxycarbonyl)Piperazine SCHEMBL3660147 | 0.81 | PLAU (0.58) | PLAUPLGF10F2ST14 | |
| SCHEMBL4556761 | 0.77 | PLAU (0.43) | PLAUPLGF10F2ST14 | |
| N-(Ethoxycarbonyl)Piperazine SCHEMBL2880394 | 0.77 | PLAU (0.63) | PLAUPLGF10F2ST14 | |
| N-(Ethoxycarbonyl)Piperazine SCHEMBL1809303 | 0.77 | PLAU (0.67) | PLAUPLGF10F2ST14 | |
| SCHEMBL4556596 | 0.76 | PLAU (0.41) | PLAUPLGF10F2ST14 | |
| N-(Ethoxycarbonyl)Piperazine SCHEMBL2875579 | 0.76 | PLAU (0.61) | PLAUPLGF10F2ST14 | |
| N-(Ethoxycarbonyl)Piperazine SCHEMBL2875164 | 0.75 | PLAU (0.65) | PLAUPLGF10F2ST14 | |
| SCHEMBL2954061 | 0.75 | PLAU (0.52) | PLAUPLGF10F2ST14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1525195-A2 | METHOD FOR THE PRODUCTION OF PHENYLALANINE DERIVATIVES | Wilex AG (DE) | 2005-04-27 | — | — | EP | claimed |
| WO-2004011449-A2 | METHOD FOR THE PRODUCTION OF PHENYLALANINE DERIVATIVES | WILEX AG (DE) | 2004-02-05 | — | — | WO | claimed |