Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 3/20 | 0.47 |
| ▸ | MME | P08473 | 5/20 | 0.42 |
| ▸ | TERT | O14746 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 4/20 | 0.36 |
| ▸ | CA1 | P00915 | 3/20 | 0.36 |
| ▸ | QRFPR | Q96P65 | 2/20 | 0.36 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.34 |
| ▸ | FNTA | P49354 | 1/20 | 0.34 |
| ▸ | FNTB | P49356 | 1/20 | 0.34 |
| ▸ | GNPAT | O15228 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1229828 | 1.00 | TGFBR1 (0.47) | TGFBR1MMETERTCA2CA1 | |
| SCHEMBL455811 | 1.00 | TGFBR1 (0.47) | TGFBR1MMETERTCA2CA1 | |
| SCHEMBL1229824 | 1.00 | TGFBR1 (0.47) | TGFBR1MMETERTCA2CA1 | |
| SCHEMBL19283433 | 1.00 | TGFBR1 (0.47) | TGFBR1MMETERTCA2CA1 | |
| SCHEMBL19283432 | 1.00 | TGFBR1 (0.47) | TGFBR1MMETERTCA2CA1 | |
| SCHEMBL29385234 | 1.00 | TGFBR1 (0.47) | TGFBR1MMETERTCA2CA1 | |
| SCHEMBL31651029 | 1.00 | TGFBR1 (0.47) | TGFBR1MMETERTCA2CA1 | |
| SCHEMBL29819412 | 1.00 | TGFBR1 (0.47) | TGFBR1MMETERTCA2CA1 | |
| SCHEMBL31488806 | 0.98 | TGFBR1 (0.48) | TGFBR1MMETERTCA2CA1 | |
| SCHEMBL4082387 | 0.98 | TGFBR1 (0.48) | TGFBR1MMETERTCA2CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 208 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117946277-A | Multispecific antibodies and methods of making and using the same | 西雅图免疫公司 | 2024-04-30 | — | — | CN | claimed |
| CN-117946278-A | Multispecific antibodies and methods of making and using the same | 西雅图免疫公司 | 2024-04-30 | — | — | CN | claimed |
| CN-110799540-B | Multispecific antibodies and methods of making and using the same | 西雅图免疫公司 | 2024-02-13 | — | — | CN | claimed |
| CN-117467017-A | Bispecific tetravalent antibodies and methods of making and using the same | 西雅图免疫公司 | 2024-01-30 | — | — | CN | claimed |
| CN-107206074-B | Bispecific tetravalent antibodies and methods of making and using the same | 西雅图免疫公司 | 2023-12-01 | — | — | CN | claimed |
| CN-116948035-A | Multispecific antibodies and methods of making and using the same | 西雅图免疫公司 | 2023-10-27 | — | — | CN | claimed |
| US-11787863-B2 | Multi-specific antibodies and methods of making and using thereof | SYSTIMMUNE, INC. | 2023-10-17 | — | — | US | claimed |
| CN-110831973-B | Multispecific antibodies and methods of making and using the same | 西雅图免疫公司 | 2023-08-15 | — | — | CN | claimed |
| CN-116199785-A | Multispecific antibodies and methods of making and using the same | 西雅图免疫公司 | 2023-06-02 | — | — | CN | claimed |
| WO-2023083381-A1 | BISPECIFIC ANTIBODY-CAMPTOTHECIN DRUG CONJUGATE AND PHARMACEUTICAL USE THEREOF | 成都百利多特生物药业有限责任公司 | 2023-05-19 | — | — | WO | claimed |
| EP-3645049-A2 | MULTI-SPECIFIC ANTIBODIES AND METHODS OF MAKING AND USING THEREOF | Systimmune, Inc. (US) | 2020-05-06 | — | — | EP | claimed |
| CN-110831973-A | Multispecific antibodies and methods of making and using the same | 西雅图免疫公司 | 2020-02-21 | — | — | CN | claimed |
| CN-110799540-A | Multispecific antibodies and methods of making and using the same | 西雅图免疫公司 | 2020-02-14 | — | — | CN | claimed |
| WO-2019005639-A2 | MULTI-SPECIFIC ANTIBODIES AND METHODS OF MAKING AND USING THEREOF | SYSTIMMUNE, INC. (US) | 2019-01-03 | — | — | WO | claimed |
| WO-2019005640-A2 | MULTI-SPECIFIC ANTIBODIES AND METHODS OF MAKING AND USING THEREOF | SYSTIMMUNE, INC. (US) | 2019-01-03 | — | — | WO | claimed |
| CN-1196791-C | Pseudomonas exotoxin-myelin basic protein chimeric proteins | YISSUM RES DEV CO (IL) | 2005-04-13 | — | — | CN | claimed |
| US-6531133-B1 | Antigen-toxin chimeric proteins useful in the targeted immunotherapy of autoimmune diseases, particularly multiple sclerosis | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) | 2003-03-11 | — | — | US | claimed |
| CN-1207132-A | Psudomonas exotoxin-myelin basic protein chimeric proteins | YISSUM RES DEV CO (IL) | 1999-02-03 | — | — | CN | claimed |
| EP-0862637-A1 | PSEUDOMONAS EXOTOXIN - MYELIN BASIC PROTEIN CHIMERIC PROTEINS | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) | 1998-09-09 | — | — | EP | claimed |
| WO-1997019179-A1 | PSEUDOMONAS EXOTOXIN - MYELIN BASIC PROTEIN CHIMERIC PROTEINS | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) | 1997-05-29 | — | — | WO | claimed |