SCHEMBL455820

SCHEMBL455820

CCc1[c]cccc1F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4680152 0.83 TAAR1 (0.31)
SCHEMBL15637364 0.81 CA1 (0.33)
SCHEMBL2141121 0.79 HDAC3 (0.35)
SCHEMBL463161 0.78 KCNH2 (0.39)
SCHEMBL18705863 0.77
SCHEMBL2072871 0.77
SCHEMBL6204663 0.77 IDO1 (0.31)
SCHEMBL19405403 0.77
SCHEMBL20487580 0.77 TAAR1 (0.37)
SCHEMBL7452456 0.77 GABRA1 (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 138 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240091303-A1 BIOMARKER-BASED TREATMENT OF FOCAL SEGMENTAL GLOMERULOSCLEROSIS AND DIABETIC KIDNEY DISEASE GOLDFINCH BIO, INC. 2024-03-21 US claimed
EP-3852533-B1 PYRIDAZINONES AND METHODS OF USE THEREOF GOLDFINCH BIO INC (US) 2024-02-28 EP claimed
US-20220152031-A1 PYRIDAZINONES AND METHODS OF USE THEREOF GOLDFINCH BIO, INC. 2022-05-19 US claimed
US-20220024917-A1 PYRIDAZINONES AND METHODS OF USE THEREOF GOLDFINCH BIO, INC. 2022-01-27 US claimed
EP-3941475-A1 PYRIDAZINONES AND METHODS OF USE THEREOF Goldfinch Bio, Inc. (US) 2022-01-26 EP claimed
CN-113939295-A Pyridazinones and methods of use thereof 金翅雀生物公司 2022-01-14 CN claimed
EP-3852533-A1 PYRIDAZINONES AND METHODS OF USE THEREOF Goldfinch Bio, Inc. (US) 2021-07-28 EP claimed
US-11046690-B2 Pyridazinones and methods of use thereof GOLDFINCH BIO, INC. (US) 2021-06-29 US claimed
CN-112911935-A Pyridazinones and methods of use thereof 金翅雀生物公司 2021-06-04 CN claimed
WO-2021067946-A1 BIOMARKER-BASED TREATMENT OF FOCAL SEGMENTAL GLOMERULOSCLEROSIS AND DIABETIC KIDNEY DISEASE GOLDFINCH BIO, INC. (US) 2021-04-08 WO claimed
WO-2020191056-A1 PYRIDAZINONES AND METHODS OF USE THEREOF GOLDFINCH BIO, INC. (US) 2020-09-24 WO claimed
US-20200283437-A1 PYRIDAZINONES AND METHODS OF USE THEREOF GFB (ABC), LLC 2020-09-10 US claimed
US-20200102301-A1 PYRIDAZINONES AND METHODS OF USE THEREOF GFB (ABC), LLC 2020-04-02 US claimed
WO-2020061162-A1 PYRIDAZINONES AND METHODS OF USE THEREOF GOLDFINCH BIO, INC. (US) 2020-03-26 WO claimed
US-20240091303-A1 BIOMARKER-BASED TREATMENT OF FOCAL SEGMENTAL GLOMERULOSCLEROSIS AND DIABETIC KIDNEY DISEASE GOLDFINCH BIO, INC. 2024-03-21 US disclosed
EP-3852533-B1 PYRIDAZINONES AND METHODS OF USE THEREOF GOLDFINCH BIO INC (US) 2024-02-28 EP disclosed
US-20220152031-A1 PYRIDAZINONES AND METHODS OF USE THEREOF GOLDFINCH BIO, INC. 2022-05-19 US disclosed
EP-0055925-A2 Alkyl N-arylsulfenyl-N-diaryloxy-phosphinylmethylglycinates and their use as herbicides MONSANTO COMPANY (US) 1982-07-14 EP disclosed
US-4300943-A Ester derivatives of N-arylthio-N-phosphonomethylglycinonitrile MONSANTO COMPANY (US) 1981-11-17 US disclosed
US-4252554-A Herbicidal ester derivatives of N-arylthio-N-phosphonomethylglycinonitrile MONSANTO COMPANY (US) 1981-02-24 US disclosed