Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 9/20 | 0.60 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.56 |
| ▸ | CNR2 | P34972 | 1/20 | 0.50 |
| ▸ | P4HTM | Q9NXG6 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | P4HA1 | P13674 | 1/20 | 0.44 |
| ▸ | MIF | P14174 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | ABL1 | P00519 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28255301 | 0.85 | P4HTM (0.47) | TRPV1P4HTMLMNAL3MBTL1NAPRT | |
| SCHEMBL4182641 | 0.83 | CNR2 (0.49) | TRPV1CNR2P4HTMLMNAL3MBTL1 | |
| SCHEMBL31426284 | 0.82 | TRPV1 (0.46) | TRPV1P4HTMLMNAL3MBTL1NAPRT | |
| SCHEMBL3554044 | 0.80 | TRPV1 (0.61) | TRPV1CYP2A6KDM4ETDP1MAPK1 | |
| SCHEMBL16114340 | 0.79 | CYP2A6 (0.67) | TRPV1CYP2A6CNR2ABL1 | |
| SCHEMBL4174480 | 0.79 | TRPV1 (0.54) | TRPV1 | |
| Hydrochloric Acid SCHEMBL3086577 | 0.79 | TRPV1 (0.59) | TRPV1CYP2A6KDM4ETDP1MAPK1 | |
| SCHEMBL8292446 | 0.77 | TRPV1 (0.81) | TRPV1 | |
| SCHEMBL13731115 | 0.76 | P4HTM (0.64) | P4HTMLMNAL3MBTL1NAPRTKDM4E | |
| SCHEMBL12817334 | 0.76 | CYP2A6 (0.62) | TRPV1CYP2A6CNR2ABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7504412-B2 | Imidazopyridine derivatives | BANYU PHARMACEUTICALS, CO., LTD. (JP) | 2009-03-17 | — | — | US | disclosed |
| US-20080200494-A1 | Imidazopyridine Derivatives | MSD K.K. (JP) | 2008-08-21 | — | — | US | disclosed |
| EP-1657242-A1 | IMIDAZOPYRIDINE DERIVATIVES | Banyu Pharmaceutical Co., Ltd. (JP) | 2006-05-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080200494-A1 | Imidazopyridine Derivatives | MC1R, MC3R, MC5R | TRPV1 183/4885CYP2A6 341/4885CNR2 177/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.