⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23660467 | 0.80 | — | — | |
| SCHEMBL10821505 | 0.80 | — | — | |
| SCHEMBL15580368 | 0.76 | TDP1 (0.33) | — | |
| SCHEMBL8848277 | 0.76 | MEN1 (0.33) | — | |
| SCHEMBL6825661 | 0.75 | TSHR (0.35) | — | |
| SCHEMBL779266 | 0.75 | ALDH1A1 (0.39) | — | |
| SCHEMBL273328 | 0.73 | — | — | |
| SCHEMBL27699936 | 0.73 | — | — | |
| SCHEMBL19302583 | 0.71 | POLB (0.63) | — | |
| SCHEMBL13137622 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090041674-A1 | TARGETED IRON OXIDE NANPARTICLES | MEDICAL RESEARCH COUNCIL (GB) | 2009-02-12 | — | — | US | disclosed |
| EP-1989547-A1 | TARGETED IRON OXIDE NANOPARTICLES | Medical Research Council (GB) | 2008-11-12 | — | — | EP | disclosed |
| WO-2007099289-A1 | TARGETED IRON OXIDE NANOPARTICLES | MEDICAL RESEARCH COUNCIL (GB) | 2007-09-07 | — | — | WO | disclosed |
| CN-1651413-A | Synthesis method of single optical isomer nitrendipine | JIAXING COLLEGE (CN) | 2005-08-10 | — | — | CN | disclosed |
| WO-1998001421-A1 | pH SENSITIVE HYDROGELS WITH ADJUSTABLE SWELLING KINETICS FOR COLON-SPECIFIC DELIVERY OF PEPTIDES AND PROTEINS | UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) | 1998-01-15 | — | — | WO | disclosed |